Exercise and Fatigue: A Public Health Approach to the Exacerbation of Post-Exertional Malaise

Dear Colleagues,

Cancer-related fatigue seems inherently similar to the fatigue experienced by those with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and now long COVID, where it is reported as post-exertional malaise (PEM). Symptoms are brought on by physical, cognitive, or emotional exertion, with commonly reported symptoms including fatigue, poor concentration, difficulty thinking, muscle pain, sleep disturbance, poor memory, flu-like feelings, joint pain, headaches, sore throat, and tender lymph nodes. Symptoms of PEM do not dissipate with rest, which contrasts with the experience of fatigue in the general healthy population, for whom physical activity is shown to not only increase energy levels but also reduce symptoms of fatigue. Given this background, papers addressing post-exertional malaise, exercise testing, and exercise training and pacing to help reduce fatigue are welcomed for this Special Issue.

Dr. Lynette Hodges
Guest Editor

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