New Perspectives in Real-World Pharmacoepidemiology and Drug Safety

Dear Colleagues,

Medicines are meant to improve patient health; however, some necessary conditions that require meeting include (i) the choice of therapy having to correspond to patient’s clinical requirements and consider patient’s characteristics, such as age, comorbidities, concomitant therapies, as well as (ii) the patient following the doctor's instructions by taking the recommended drugs at the proper doses for as long as necessary. These two assumptions can represent a challenge in daily clinical practice, especially in particularly critical and frail subpopulations such as the elderly, polytreated patients, or in complex socio-health conditions such as those determined by the recent COVID-19 pandemic. The evaluation of these aspects and the quantification of their consequences in terms of morbidity and mortality are crucial (i) to increase awareness among health decision makers concerning the epidemiological and clinical impact of an inappropriate prescription and low adherence to the own pharmacological therapies, and (ii) to design interventions to improve patients’ clinical outcomes and reduce unnecessary costs for National Health Services.

This Special Issue is dedicated to reviews and original articles addressing the issues surrounding the appropriateness of drug prescriptions, drug adherence, drug safety evaluations in real-life settings and clinical consequences on patients' health.

Dr. Carlotta Franchi
Dr. Manuela Casula
Dr. Ilaria Ardoino
Guest Editors

Manuscript Submission Information

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