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Advanced Oxidation Processes for the Decontamination of Emerging Contaminants and Disinfection of Pathogenic Microorganisms

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 838

Special Issue Editor

Special Issue Information

Dear Colleagues,

Cost-effective and environmentally friendly decontamination of emerging contaminants and the disinfection of pathogenic microorganisms are major challenges in water treatment. In this regard, advanced oxidation processes (AOPs) have been considered a promising alternative. This is because of the highly reactive radicals, such as hydroxyl, sulfate, and organic radicals, generated in AOPs that can effectively degrade emerging contaminants and inactivate pathogenic microorganisms. Nevertheless, the practical applications of AOPs are challenged by the interference of the water matrix, formation of harmful byproducts, difficulty in scaling-up, etc. Both a novel molecular mechanistic understanding and an improved engineering design are needed to overcome the challenges and create an effective transfer of academic research output and practical applications of AOPs. This Special Issue will focus on molecular studies with regard to the mechanistic understanding, development, and implementation of AOPs for the decontamination of emerging contaminants and the disinfection of pathogenic microorganisms in water treatment, including hydroxyl radical-, sulfate radical-, and organic radical-based AOPs. We welcome your submissions of original papers and reviews based on results from molecular viewpoints.

Dr. Chengdu Qi
Guest Editor

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Keywords

  • advanced oxidation processes
  • emerging contaminants
  • pathogenic microorganisms
  • disinfection
  • hydroxyl radical
  • sulfate radical
  • organic radical

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Published Papers (1 paper)

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Research

15 pages, 4521 KiB  
Article
Environmentally Friendly UV Absorbers: Synthetic Characterization and Biosecurity Studies of the Host–Guest Supramolecular Complex
by Luwei Tian, Yanan Wu, Yetong Hou, Yaru Dong, Kaijie Ni and Ming Guo
Int. J. Mol. Sci. 2024, 25(15), 8476; https://doi.org/10.3390/ijms25158476 - 3 Aug 2024
Viewed by 645
Abstract
Isoamyl 4-methoxycinnamate (IMC) is widely used in various fields because of its exceptional UV-filter properties. However, due to its cytotoxicity and anti-microbial degradability, the potential eco-environmental toxicity of IMC has become a focus of attention. In this study, we propose a host–guest supramolecule [...] Read more.
Isoamyl 4-methoxycinnamate (IMC) is widely used in various fields because of its exceptional UV-filter properties. However, due to its cytotoxicity and anti-microbial degradability, the potential eco-environmental toxicity of IMC has become a focus of attention. In this study, we propose a host–guest supramolecule approach to enhance the functionality of IMC, resulting in a more environmentally friendly and high-performance materials. Sulfobutyl-β-cyclodextrin sodium salt (SBE-β-CD) was used as the host molecule. IMC-SBE-β-CD supramolecular substances were prepared through the “saturated solution method”, and their properties and biosecurity were evaluated. Meanwhile, we conducted the AOS tree evaluation system that surpasses existing evaluation approaches based on apoptosis, oxidative stress system, and signaling pathways to investigate the toxicological mechanisms of IMC-SBE-β-CD within human hepatoma SMMC-7721 cells as model organisms. The AOS tree evaluation system aims to offer the comprehensive analysis of the cytotoxic effects of IMC-SBE-β-CD. Our findings showed that IMC-SBE-β-CD had an encapsulation rate of 84.45% and optimal stability at 30 °C. Further, IMC-SBE-β-CD promoted cell growth and reproduction without compromising the integrity of mitochondria and nucleus or disrupting oxidative stress and apoptosis-related pathways. Compared to IMC, IMC-SBE-β-CD is biologically safe and has improved water solubility with the UV absorption property maintained. Our study provides the foundation for the encapsulation of hydrophobic, low-toxicity organic compounds using cyclodextrins and offers valuable insights for future research in this field. Full article
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