Research Advances in Retinal Neurodegeneration and Neuroprotection Strategies
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 31 December 2024 | Viewed by 55
Special Issue Editors
Interests: retina; neurodegeneration; neuroprotection; retinal pigment epithelium; retinal function; age related macular degeneration; nanoparticles
Special Issues, Collections and Topics in MDPI journals
Interests: retina; neurodegeneration; neuroprotection; retinal pigment epithelium; retinal function; age related macular degeneration; retinal organoids; hESCs; iPSCs
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue of The International Journal of Molecular Sciences will provide an update on retinal neurodegenerative diseases and neuroprotective strategies. The dramatic increase in the number of patients suffering from retinal disorders has compelled expert research groups in this field to focus their efforts on identifying new therapeutic targets and developing protective strategies. This topic spans several fields, including physiology, neuroscience, pathology, and pharmacology. The main retinal neurodegenerative diseases caused by harmful environmental stimuli or genetic mutations include Age-Related Macular Degeneration, Glaucoma, Leber's Congenital Amaurosis, Retinitis Pigmentosa, Retinoschisis, Stargardt's Disease, and Usher Syndrome. To date, many molecular and physiological mechanisms linked to retinal disorders and vision loss have been identified, including pathways involved in the dysfunction of epithelial cells, photoreceptor and ganglion cells death, oxidative stress, autophagy dysfunction, inflammatory markers, retinal immune system impairment, the breakdown of the blood–retinal barrier, and retinal detachment. Despite the vast scientific literature available, further studies are necessary to increase our knowledge of still unknown mechanisms related to different pathologies. Furthermore, since the retina is part of the central nervous system, and its neuronal circuitry, glial cells, and vasculature and immunocompetent systems recapitulate the functionality of many areas of the brain, the identification of early biomarkers of other neurodegenerative disorders in the retina could be beneficial. We encourage authors to submit original research articles, reviews, or short communications documenting in vitro and in vivo preclinical studies. Well-documented strategies that counteract vision loss, ranging natural compounds, small molecules, nanoparticles, antibodies, peptides, gene therapy, exosomes, etc., will be welcome in this Special Issue. Publishing an article in this Special Issue provides a great opportunity to join a community of experts in this field.
Dr. Maccarone Rita
Dr. Darin Zerti
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- retinal neurodegeneration
- retinal neuroprotection
- retinal pigment epithelium dysfunction
- electrophysiology
- molecular targets
- drug delivery
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
