The Role and Mechanism of P2X7 Receptor in Cancer and Inflammatory Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: closed (30 July 2024) | Viewed by 2297
Special Issue Editor
Interests: cancer research; cell culture; immunology; molecular biology; cancer biology; signaling pathways; cell biology; antibodies; inflammation; flow cytometry
Special Issue Information
Dear Colleagues,
The purpose of this Special Issue is to summarize the roles and mechanisms of P2X7 receptors in human diseases, particularly in cancer and inflammatory diseases. The P2X7 receptor is an ATP-gated non-selective cation channel that is widely expressed in a variety of immune and nonimmune cells. P2X7 receptors play a key role in inflammation and immunomodulation, such as signal transduction and the activation of immune cells. The activity of P2X7 receptors in tumour growth and dissemination is also of interest. The awareness about the role of P2X7 in human diseases and the consideration of the P2X7 receptor as a potential target for the treatment of inflammatory diseases and cancer are constantly increasing.
This Special Issue aims to publish high-quality manuscripts that provide insights into the molecular mechanisms of P2X7 receptors in cancer and inflammatory diseases.
Dr. Anna Lisa Giuliani
Guest Editor
Manuscript Submission Information
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Keywords
- P2X7 receptor
- inflammation
- cancer
- purinergic signalling
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