ijms-logo

Journal Browser

Journal Browser

Recent Progress in Neuro-Oncology and Neuro-Inflammation: Novel Diagnostic and Therapeutic Tools

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".

Deadline for manuscript submissions: 30 July 2024 | Viewed by 1310

Special Issue Editor


E-Mail Website
Guest Editor
Nuclear Medicine Unit, Cardarelli Hospital, Campobasso, Italy
Interests: nuclear medicine; oncology neurology; theranostic; positron emission tomography
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are pleased to announce the upcoming Special Issue of IJMS, entitled “Recent Progress in Neuro-Oncology and Neuro-Inflammation: Novel Diagnostic and Therapeutic Tools”, published in the open access journal International Journal of Molecular Sciences (IF 5.6).

Over the last years, novel diagnostic and therapeutic tools have been investigated in neuro-oncology and neuro-inflammation fields, both in research and in practice settings. These have played a major role in terms of precision medicine. Moreover, novel diagnostics and therapeutic molecules, either alone or in combination with further biomarkers, may provide novel insights in the fields of neuro-oncology and neuro-inflammation. The aim of this Special Issue is to seek interesting papers on novel techniques and tools, new advances, and suggestions for future research in these important fields, with a special focus on molecular mechanical studies.

We would like to invite you to publish your next paper in this Special Issue. Long review papers focused on molecular mechanical studies and original research articles are welcome.

We look forward to receiving your contributions.

Dr. Maria Ricci
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • neuro-oncology
  • neuro-inflammation
  • diagnostic and therapeutic tools

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Review

27 pages, 1135 KiB  
Review
Recurrent Glioblastoma—Molecular Underpinnings and Evolving Treatment Paradigms
by Christopher Chang, Velina S. Chavarro, Jakob V. E. Gerstl, Sarah E. Blitz, Lennard Spanehl, Daniel Dubinski, Pablo A. Valdes, Lily N. Tran, Saksham Gupta, Luisa Esposito, Debora Mazzetti, Florian A. Gessler, Omar Arnaout, Timothy R. Smith, Gregory K. Friedman, Pierpaolo Peruzzi and Joshua D. Bernstock
Int. J. Mol. Sci. 2024, 25(12), 6733; https://doi.org/10.3390/ijms25126733 - 19 Jun 2024
Viewed by 922
Abstract
Glioblastoma is the most common and lethal central nervous system malignancy with a median survival after progression of only 6–9 months. Major biochemical mechanisms implicated in glioblastoma recurrence include aberrant molecular pathways, a recurrence-inducing tumor microenvironment, and epigenetic modifications. Contemporary standard-of-care (surgery, radiation, [...] Read more.
Glioblastoma is the most common and lethal central nervous system malignancy with a median survival after progression of only 6–9 months. Major biochemical mechanisms implicated in glioblastoma recurrence include aberrant molecular pathways, a recurrence-inducing tumor microenvironment, and epigenetic modifications. Contemporary standard-of-care (surgery, radiation, chemotherapy, and tumor treating fields) helps to control the primary tumor but rarely prevents relapse. Cytoreductive treatment such as surgery has shown benefits in recurrent glioblastoma; however, its use remains controversial. Several innovative treatments are emerging for recurrent glioblastoma, including checkpoint inhibitors, chimeric antigen receptor T cell therapy, oncolytic virotherapy, nanoparticle delivery, laser interstitial thermal therapy, and photodynamic therapy. This review seeks to provide readers with an overview of (1) recent discoveries in the molecular basis of recurrence; (2) the role of surgery in treating recurrence; and (3) novel treatment paradigms emerging for recurrent glioblastoma. Full article
Show Figures

Figure 1

Back to TopTop