Lipidomics of Human Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Macromolecules".
Deadline for manuscript submissions: closed (15 April 2024) | Viewed by 7443
Special Issue Editors
Interests: lipid immunology
Special Issue Information
Dear Colleagues,
Long Chain Poly Unsaturated Fatty Acids (LC-PUFAs) have been recognized as modulators of the immune system for a long time. The balance between ω-3 and ω-6 LC-PUFAs is thought to influence the overall characteristics of the immune response. Despite the extensive research on the anti-inflammatory nature of the most common ω-3 LC-PUFAs, DHA and EPA, establishing an optimal balance between the various ω-3 and ω-6 LC-PUFAs has been challenging. Our understanding of how LC-PUFAs are depleted during chronic infections is limited. Peroxidation of LC-PUFAs during digestion and the impact on their bioavailability is another area of continued research. Formulations of LC-PUFAs that minimize peroxidation and increase bioavailability is an additional area under exploration.
The objective of this special issue is to bring together the most current research findings relating to LC-PUFAs and their influence on the immune system.
Dr. Evros Vassiliou
Dr. Rana Zeine
Guest Editors
Manuscript Submission Information
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Keywords
- docosahexaenoic acid
- eicosapentaenoic acid
- arachidonic acid
- inflammation
- prostaglandins
- apoptosis
- bioavailability
- peroxidation
- reactive oxygen species
