ijms-logo

Journal Browser

Journal Browser

Oral Soft Tissue Repair and Oral Diseases: 2nd Edition

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".

Deadline for manuscript submissions: 30 August 2025 | Viewed by 529

Special Issue Editor

Special Issue Information

Dear Colleagues,

We are delighted to invite you to submit a manuscript to the 2nd edition Special Issue of “Oral Soft Tissue Repair and Oral Diseases”, for the International Journal of Molecular Sciences.

This Special Issue covers a wide range of topics related to the use of modern devices and materials in medicine and dentistry across different levels of research, from basic and applied science to laboratory, pre-clinical, and clinical studies. The Special Issue involves studies at a molecular level of how to apply new advanced devices, e.g., The research on Endoret and exogenous system in oral tissue regeneration, using patients' own bioactive proteins, growth factors and biomaterial scaffolds for treatment, which provides a new way to stimulate and accelerate tissue healing and bone regeneration. Lipid nanoparticle coated nucleoside modified messenger RNA (mRNA) platforms have been evaluated in various models of soft and hard tissue regeneration, such as myocardial infarction, and have shown promising results. In addition, platelet-rich preparations constitute relatively new biotechnologies that stimulate and accelerate tissue healing and bone regeneration. The versatility and biocompatibility of this method stimulate its application in tissue regeneration. Finally, studies that help to better understand how we can decrease bacterial, viral, and fungal contamination in the healthcare environment will be considered for publication in this issue.

Dr. Jacek Matys
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • oral medicine
  • tissue regeneration
  • lasers
  • photobiomodulation
  • periodontology
  • implant dentistry

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue policies can be found here.

Related Special Issue

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Review

19 pages, 907 KiB  
Review
Fatty Degenerative Osteonecrosis of the Jaw: Bridging Molecular Insights and Clinical Practice—A Scoping Review
by Marzena Dominiak, Wojciech Niemczyk, Artur Pitułaj, Witold Świenc and Jacek Matys
Int. J. Mol. Sci. 2025, 26(5), 1853; https://doi.org/10.3390/ijms26051853 - 21 Feb 2025
Viewed by 246
Abstract
Fatty degenerative osteonecrosis of the jaw (FDOJ) is a chronic, aseptic inflammatory condition that is characterized by molecular disruptions in bone metabolism and necrotic bone marrow within the jawbone cavities. In contrast to the overt clinical signs typically observed in osteopathies, FDOJ frequently [...] Read more.
Fatty degenerative osteonecrosis of the jaw (FDOJ) is a chronic, aseptic inflammatory condition that is characterized by molecular disruptions in bone metabolism and necrotic bone marrow within the jawbone cavities. In contrast to the overt clinical signs typically observed in osteopathies, FDOJ frequently presents with a “silent inflammation” phenotype. The electronic databases PubMed, Scopus, and Embase were searched using appropriate search terms, and the methodology was performed according to PRISMA-ScR guidelines. The elevated expression of inflammatory mediators, particularly C-C motif Chemokine Ligand-5/Regulated on Activation, Normal T Cell Expressed and Secreted (CCL5/RANTES), fibroblast growth factor-2, and interleukin-1 receptor antagonist, distinguishes FDOJ at the molecular level and links it to systemic inflammatory and autoimmune diseases. These immunohistochemical markers play a pivotal role in the pathogenesis of chronic inflammation, immune response regulation, and abnormal bone remodeling. Advanced diagnostic tools, such as conebeam computed tomography and trans-alveolar ultrasonography, facilitate the detection of pathological changes that are not easily discernible with conventional radiography. Surgical intervention remains the primary treatment modality, often complemented by therapies that target these molecular pathways to modulate chronic inflammation. This article underscores the importance of integrating molecular diagnostics, advanced imaging, and clinical data for effective FDOJ detection and management. Full article
(This article belongs to the Special Issue Oral Soft Tissue Repair and Oral Diseases: 2nd Edition)
Show Figures

Figure 1

Back to TopTop