The Role of Cytokines in Diseases

Dear Colleagues,

Cytokines are a diverse group of proteins that are critical for regulating immune responses and inflammation as they facilitate communication between immune cells in response to various stimuli, including pathogens, tissue damage, and cancer cells. An imbalance in cytokine production and activity can lead to autoimmune disorders, chronic inflammation, and cancer.

The activation of cytokines is essential for initiating and maintaining immune responses to pathogen-associated patterns. Various immune cells, such as macrophages, dendritic cells, and T cells, produce cytokines influenced by the nature of pathogen-associated patterns, genetics, and environmental exposure.

We invite the submission of original research papers, case reports, clinical trials, and review articles on the following potential topics:

1. Molecular regulation of cytokine activation.
2. Cytokine roles in infection, cancer, and autoimmune disease pathogenesis.
3. Molecular mechanisms of novel therapeutic approaches targeting cytokines.
4. Monoclonal antibodies for treatment of cytokine-associated disorders.
5. Genetic and epigenetic factors contributing to cytokine activation.
6. The role of PAMPS, DAMPS, and PRRs in cytokine activation.
7. Environmental factors influencing cytokine activation.

Dr. Svetlana Khaiboullina
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.