Novel Approaches for Topical or Transdermal Delivery of Large Molecules
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: closed (15 July 2024) | Viewed by 3089
Special Issue Editors
Interests: pharmaceutical development; pharmaceutics and pharmaceutical technology
Special Issue Information
Dear Colleagues,
Topical/transdermal drug delivery is ideal for delivering many active pharmaceutical ingredients (APIs), including insulin and antibodies, because of its unique advantage of bypassing the first-pass metabolism and protection from enzyme degradation in the gastrointestinal tract. Although significant advances have been made in the field of topical/transdermal drug delivery, there are only a few products in the market approved by the FDA. Patients suffering from certain diseases, including diabetes and cancer, require a convenient dosage form instead of painful injections. Therefore, there is an urgent need to explore novel strategies for transdermal delivery of large molecules.
Dr. Arvind Bagde
Prof. Dr. Shawn D Spencer
Guest Editors
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Keywords
- topical
- insulin
- proteins
- antibodies
- transdermal
- microneedle
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