Heart Failure Risk Factors and Therapies-Molecular Basis
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 April 2025 | Viewed by 41
Special Issue Editor
Interests: heart transplantation; LVAD; MCS; heart failure; immunology; rejection
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The inflammatory background of heart failure (HF) development and progression has gained much attention in recent times.
As HF is a complex disease presenting clinical challenges for current populations, the proper understanding of the processes that drive its progression is of utmost importance.
The risk factors that lead to immunological system activation, a key aspect of HF development, is one of the Special Issue topic goals. The pathophysiological link between nontraditional risk considerations of HF is the subject of the investigation in the Special Issue. The environmental-related risk elements due to the fast developing industrial and climate changes are among the Special Issue interests. This Special Issue aims to present possible molecular explanations for exposure factors, including air pollutant particles and mechanisms that lead to HF by inflammatory activation.
Within the Special Issue, interest is not only focused at the molecular explanation of triggering factors, but also at understanding processes involved in HF progression. A better understanding of cellular involvement, including neutrophils and their derived particles, and how their released cytokines contribute to triggering further processes and even trace elements content may broaden our horizons in the subject.
The pharmacological and interventional therapies, which have improved patient outcomes, are a growing interest in the field of HF research. The medical treatments next to mechanical support improve patients’ clinical status and prognosis and may induce various molecular-based processes in the organisms that are among the interests of this Special Issue.
The research areas for exploration:
- Molecular mechanisms in HF;
- Molecular mechanisms secondary to non-traditional HF risk factors;
- Molecular mechanisms triggered by air pollution in HF patients;
- Molecular mechanisms on medical HF therapy;
- Molecular mechanisms triggered by mechanical support.
Dr. Tomasz Urbanowicz
Guest Editor
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Keywords
- heart failure
- risk factors
- inflammatory
- neutrophils
- cytokines
- pharmacological
- therapies
- molecular-based processes
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