Bone Biomaterials Research and 3D Spheroid Culture Systems in Osteogenesis

Dear Colleagues,

Various methods for bone research have been suggested, and many studies have focused on the most suitable materials and research methods for living organisms. However, it is still difficult to create standardized data according to the experimental environment and materials. To overcome this, a Special Issue dedicated to the intersection of “Bone Biomaterials Research and 3D Spheroid Culture Systems in Osteogenesis”, is a field poised to revolutionize our understanding of bone tissue engineering. This thematic collection aims to provide a comprehensive platform for researchers to explore the intricate molecular mechanisms underpinning osteogenesis within the context of 3D spheroid culture systems.

The interaction of bone biomaterials and 3D spheroid culture techniques represents a groundbreaking approach, offering unique insights into the complex interplay between cells, biomaterials, and their microenvironment during bone regeneration. This Special Issue invites researchers to contribute your original work, spanning from material design and fabrication processes to in-depth investigations into the molecular mechanisms governing osteogenic differentiation within 3D spheroid cultures.

As we delve into the molecular intricacies of osteogenesis, contributors are encouraged to explore themes such as signaling pathways, gene expression profiles, and cell-cell interactions that influence the fate of osteoprogenitor cells in 3D culture systems. We anticipate that this Special Issue will serve as a catalyst for innovative research at the crossroads of bone biomaterials and 3D spheroid cultures, fostering collaboration and driving advancements in regenerative medicine.

Researchers from diverse backgrounds are invited to submit their cutting-edge contributions, fostering a vibrant exchange of ideas and accelerating the translation of discoveries into practical applications. Together, let us unravel the mysteries of bone biomaterials and 3D spheroid culture systems, paving the way for transformative developments in the realm of osteogenesis research.

Dr. Chawon Yun
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• osteogenic differentiation
• 3D culture
• bone regeneration
• toxicological and pharmacological assessment
• bone homeostasis
• bone materials