Virus Engineering and Applications: 3rd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".
Deadline for manuscript submissions: 31 March 2025 | Viewed by 381
Special Issue Editor
Interests: oncolytic herpes simplex virus; tropism retargeting; cancer receptors; virus engineering; virus arming; virus-mediated transgene expression
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The recent SARS-CoV-2 pandemic recalled and focused worldwide attention, perception, and awareness on viruses and highlighted the global need to prepare for future emerging threats. At present, this is just the most exposed facet of the virus world. However, viruses are much more. Virus engineering is a well-established discipline, both as a tool and as a research subject, and it is now receiving attention at the intersection with novel, expanding omics breakthroughs. Thus, the possibility to retrieve viral sequences from the most diverse matrices expanded the boundaries of the virosphere in an unprecedented way. Here, virus engineering comes into play, allowing for the study of the biological properties of viral entities, or just the parts thereof, that have not been isolated as particles or whose host is not known, with tremendous implications both in ecology and global health. Virus engineering allows for reviving both known extinct or unknown possible pathogens, variants of concern, etc., and designing and devising countermeasures, drugs, or vaccines, with a constant eye on ethics and safety issues. Virus engineering allows for shedding light on virus origin, emergence, and evolution as well. Finally, an ever-growing body of knowledge builds up for increasingly sophisticated viruses engineered as therapeutic platforms themselves, for gene therapy, oncolytic virotherapy, or bio-nanomaterials. In this regard, submissions of original research papers, perspectives, and reviews are welcome for this Special Issue. Topics of interest include, but are not limited to:
- Basic virology;
- Viral biotechnology;
- Virus engineering platforms, toolboxes, and technologies;
- Viral vaccine platforms;
- Viral gene therapy;
- Oncolytic virotherapy and immunovirotherapy;
- Personalized medicine with virus-based biologicals;
- Ethics of virus engineering;
- Virus origin, emergence, and evolution;
- Viral synthetic biology;
- Virus metagenomics and the virosphere;
- Virus-based bio-nanomaterials and bio-nanotechnologies.
Dr. Laura Menotti
Guest Editor
Manuscript Submission Information
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Keywords
- virus engineering
- oncolytic virotherapy
- immunovirotherapy
- viral biotechnology
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