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New Head and Neck Surgery under Precise Notion: Technology, Theory...
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New Head and Neck Surgery under Precise Notion: Technology, Theory and Practice

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Otolaryngology".

Deadline for manuscript submissions: closed (25 November 2023) | Viewed by 4387

Special Issue Editors

Dr. Lin-Lin Bu

E-Mail Website
Guest Editor
Department of Oral Maxillofacial Head Neck Oncology, School and Hospital of Stomatology, Wuhan University, Wuhan, 430079, China
Interests: complicated head neck oncology; head & neck reconstruction surgery
Special Issues, Collections and Topics in MDPI journals
Dr. Bing Liu

E-Mail Website
Guest Editor
1. The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China
2. Department of Oral and Maxillofacial Head Neck Oncology, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China
Interests: oral diseases; oral squamous cell carcinoma; extracellular vesicles; molecular marker; microRNAs
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Head and neck cancer (HNC) is a relatively rare type of cancer that has serious repercussions on patients' quality of life. The traditional radical resection of HNC simply pursues the complete removal of the tumor but leaves huge functional and aesthetic defects. With the continuous innovation of surgical technology and concept, the surgical treatment of HNC has entered a new era of precise notion with simultaneous resection and reconstruction, and both aesthetics and function. The goal of HNC surgery in the new stage is to implement the concept of ERAS, and preserve the life quality of patients.

Technological progress such as microscope, endoscope, robot, navigation, CAD/CAM surgical guide template, artificial intelligence, virtual reality technology, tissue engineering, etc., has laid the foundation for surgical innovation. These advanced technologies have essentially changed the procedure of HNC surgery, making minimally invasive, precise and functionally preserved surgery a reality.

Continuous in-depth understanding of tumor pathology and human physiology theoretically changed the surgeon's concept of surgery. The recognition of tumor margin, lymph node metastasis, donor function recovery, patient psychology and other issues has led clinicians to pursue precise resection and reconstruction to improve the quality of life of patients after surgery.

Taken together, a series of clinical practice such as intraoral anastomosis technique, microvascular iliac flap, ERAS concept, etc., came into being under the precise notion of HNC surgery. With the rapid and vigorous development of precision surgery, greater interests have emerged in the whole process of HNC treatment such as innovative techniques, modified surgery management, perioperative nursing, psychological intervention, medical training, etc.

This Special Issue, entitled “New Head and Neck Surgery under Precise Notion: Technology, Theory and Practice”, aims to explore innovations regarding precise approach in head and neck cancer treatment.

The specific topics that we are interested in are:

  • Innovative techniques, i.e., surgical robot, artificial intelligence, tissue engineering, endoscopic surgery, computer aided technology, flap monitoring techniques, etc.
  • Modified surgery management, i.e., intraoral anastomosis technique, microvascular iliac flap, flap prefabrication, lymph node dissection strategy, surgical margins, aesthetic and functional considerations of reconstruction, etc.
  • Multidisciplinary research, i.e., perioperative nursing, psychological intervention, enhanced recovery after surgery (ERAS), medical training, etc.

Dr. Lin-Lin Bu
Dr. Bing Liu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • head and neck cancer
  • head and neck surgery
  • new technologies in surgery
  • modified surgery management
  • multidisciplinary cooperation

Published Papers (3 papers)

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Research

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14 pages, 3170 KiB  
Article
A Full View of Papillary Craniopharyngioma Based on Expanded Endonasal Approach: A Comprehensive Clinical Characterization of 101 Cases
by Yanfei Jia, Kefan Cai, Ning Qiao, Fangzheng Liu, Wentao Wu, Siming Ru, Youchao Xiao, Lei Cao and Songbai Gui
J. Clin. Med. 2023, 12(20), 6551; https://doi.org/10.3390/jcm12206551 - 16 Oct 2023
Viewed by 899
Abstract
Objective: The enlarged endonasal approach (EEA) has emerged as the preferred surgical procedure for removing craniopharyngiomas, due to its advantages of direct visualization and reduction of blind corners. However, owing to a low incidence of papillary CPs (PCPs) compared to adamantinomatous CPs (ACPs), [...] Read more.
Objective: The enlarged endonasal approach (EEA) has emerged as the preferred surgical procedure for removing craniopharyngiomas, due to its advantages of direct visualization and reduction of blind corners. However, owing to a low incidence of papillary CPs (PCPs) compared to adamantinomatous CPs (ACPs), a full view of PCP based on the EEA approach is limited. In this paper, the authors present the largest series to date analyzing the clinical characteristics based on the EEA approach for PCPs. Methods: A retrospective review was conducted on 101 PCPs patients who underwent endoscopic endonasal surgery (EEA) and whose condition was confirmed via postoperative pathology. The PCPs were classified into three types based on MRI data and intraoperative findings from EEA: suprasellar/intra-suprasellar (3V floor intact) type (Type I), suprasellar/intra-suprasellar (3V floor invasive) type (Type II), and intra-third ventricle type (Type III). The general characteristics of the three types of tumors were summarized, and postoperative follow-up was conducted to record detailed information on changes in vision, endocrine replacement, tumor recurrence, and quality of life. Results: Out of the 101 cases, 36 (36.64%) were classified as type I, 52 (51.49%) as type II, and 13 (12.87%) as type III. The mean age of type III patients was 40.46 ± 14.15 years old, younger than the other two types (p = 0.021). Headache (84.62%) and memory decline (61.54%) were prominent features in patients with type III (p = 0.029). Visual impairment was more common in type II (80.77%, p = 0.01). Gross total resection (GTR) was achieved in 91 patients (90.10%). There were no significant differences in GTR rates among the three types of tumors. There were significant differences in quality of life among the three types of PCP (p = 0.004), and type III presented with the highest rate of good postoperative quality of life (92.31%) based on the KPS score. Thirteen (12.87%) tumors recurred within a mean follow-up time of 38 (range, 8–63) months. Type II PCPs (OR 5.826, 95%CI 1.185–28.652, p = 0.030) and relapsed patients (OR 4.485, 95%CI 1.229–16.374, p = 0.023) were confirmed as independent risk factors for tumor recurrence. Conclusions: Most of the PCPs including intra-third ventricle PCPs can be safely and effectively removed through neuroendoscopy with EEA. Suprasellar/intra-suprasellar (third cerebral ventricle floor-invasive) type PCPs may have a worse postoperative quality of life compared to the other two types, and it may be a strong predictor of tumor recurrence. Full article
(This article belongs to the Special Issue New Head and Neck Surgery under Precise Notion: Technology, Theory and Practice)
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Review

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16 pages, 2040 KiB  
Review
Salivary Gland Transplantation as a Promising Approach for Tear Film Restoration in Severe Dry Eye Disease
by Jiayi Chen, Tianyi Bai, Jiazeng Su, Xin Cong, Lan Lv, Louis Tong, Haozhe Yu, Yun Feng and Guangyan Yu
J. Clin. Med. 2024, 13(2), 521; https://doi.org/10.3390/jcm13020521 - 17 Jan 2024
Viewed by 1178
Abstract
With increased awareness of dry eye disease (DED), a multitude of therapeutic options have become available. Nevertheless, the treatment of severe DED remains difficult. In a patient whose DED is related to the loss of lacrimal function without severe destruction of the salivary [...] Read more.
With increased awareness of dry eye disease (DED), a multitude of therapeutic options have become available. Nevertheless, the treatment of severe DED remains difficult. In a patient whose DED is related to the loss of lacrimal function without severe destruction of the salivary glands, autologous transplantation of the latter as functioning exocrine tissue to rebuild a stable tear film is an attractive idea. All three major and minor salivary glands have been used for such transplantation. Due to the complications associated with and unfavorable prognosis of parotid duct and sublingual gland transplantation, surgeons now prefer to use the submandibular gland (SMG) for such procedures. The transplantation of the SMG not only has a high survival rate, but also improves dry eye symptoms and signs for more than 20 years post-surgery. The regulation of the secretion of the transplanted SMG is critical because the denervated SMG changes its mechanism of secretion. Innovative procedures have been developed to stimulate secretion in order to prevent the obstruction of the Wharton’s duct and to decrease secretion when postoperative “epiphora” occurs. Among the minor salivary glands, the transplantation of the labial salivary glands is the most successful in the long-term. The measurement of the flow rates of minor salivary glands and donor-site selection are critical steps before surgery. Full article
(This article belongs to the Special Issue New Head and Neck Surgery under Precise Notion: Technology, Theory and Practice)
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22 pages, 1114 KiB  
Review
Image-to-Patient Registration in Computer-Assisted Surgery of Head and Neck: State-of-the-Art, Perspectives, and Challenges
by Ali Taleb, Caroline Guigou, Sarah Leclerc, Alain Lalande and Alexis Bozorg Grayeli
J. Clin. Med. 2023, 12(16), 5398; https://doi.org/10.3390/jcm12165398 - 19 Aug 2023
Cited by 3 | Viewed by 1690
Abstract
Today, image-guided systems play a significant role in improving the outcome of diagnostic and therapeutic interventions. They provide crucial anatomical information during the procedure to decrease the size and the extent of the approach, to reduce intraoperative complications, and to increase accuracy, repeatability, [...] Read more.
Today, image-guided systems play a significant role in improving the outcome of diagnostic and therapeutic interventions. They provide crucial anatomical information during the procedure to decrease the size and the extent of the approach, to reduce intraoperative complications, and to increase accuracy, repeatability, and safety. Image-to-patient registration is the first step in image-guided procedures. It establishes a correspondence between the patient’s preoperative imaging and the intraoperative data. When it comes to the head-and-neck region, the presence of many sensitive structures such as the central nervous system or the neurosensory organs requires a millimetric precision. This review allows evaluating the characteristics and the performances of different registration methods in the head-and-neck region used in the operation room from the perspectives of accuracy, invasiveness, and processing times. Our work led to the conclusion that invasive marker-based methods are still considered as the gold standard of image-to-patient registration. The surface-based methods are recommended for faster procedures and applied on the surface tissues especially around the eyes. In the near future, computer vision technology is expected to enhance these systems by reducing human errors and cognitive load in the operating room. Full article
(This article belongs to the Special Issue New Head and Neck Surgery under Precise Notion: Technology, Theory and Practice)
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