Advances in Molecular and Cellular Studies in Oral Diseases

Dear Colleagues,

Oral diseases are a major global health problem with significant social and economic impacts that can affect overall health, psychosocial well-being and human quality of life. A thorough understanding of the pathogenesis, diagnosis and treatment of different oral diseases is essential to maintain oral health. Extracellular vesicles (EVs), which carry DNAs, proteins, mRNAs and microRNAs, have been characterized as novel, potential clinical agents for disease diagnosis, prognosis, therapy and drug delivery owing to their ability to transfer bioactive molecules among various cells. Oral squamous cell carcinoma (OSCC) cells can transfer genetic information and modulate cell signaling in other cells through the release of EVs. To date, it has been known that OSCC cells derive from EVs containing proteins or microRNAs that inhibit immune response and contribute to tumor progression. Therefore, inhibiting EV secretion by tumor cells has been considered as an effective therapeutic target for cancers and odontogenic tumors. This Topic will be entitled, “Advances in Molecular and Cellular Studies in Oral Diseases”, and will focus on discussing pathogenesis, molecular targets and therapeutics treatment for oral diseases. We welcome you to share experimental papers and the latest review articles with new data.

Dr. Bing Liu
Prof. Dr. Ming Zhong
Topic Editors