Chronic Wounds or Hard to Heal Ulcers: Updating Epidemiology, Physiopathology, and Therapies-Part II

Dear Colleagues,

In December 2020, the first volume of the Special Issue “Chronic Wounds or Hard-to-Heal Ulcers: Updating Epidemiology, Physiopathology, and Therapies” was launched (https://www.mdpi.com/journal/jcm/special_issues/hard_to_heal_ulcers), and we received many excellent papers on the prevention and management of chronic wounds. Now, we would like to launch a second volume on this topic.

Currently, there is intense debate about the terminology, etiology, and epidemiology of so-called chronic wounds, and about current strategies for their prevention and management. Researchers usually use terms such as “chronic wound”, “skin ulcer”, and “hard-to-heal wound or ulcer” indistinctly. However, for certain types of wound, the terminology is changing due to new insights into their physiopathology and etiology; this has led to new theoretical models of wound development, for instance, the progression from decubitus or bed sores to pressure ulcers, and then, to pressure injuries. The case is similar for leg or lower-extremity wounds, where different etiologies could be present.

Nevertheless, many people suffer from such lesions, experiencing a direct cost burden, as well as indirect impacts such as decreased quality of life for themselves and their families. On the other hand, the current prevention and treatment strategies are still limited and are often less effective, or there is little evidence to support them.

This highlights the urgent need for new approaches and new, higher-quality research, requiring further understanding of the whole process, from etiology to wound healing.

In this Special Issue of the Journal of Clinical Medicine on chronic or hard-to-heal wounds, we intend to present cutting-edge original research and systematic, integrative, or scoping reviews on the epidemiology, risk factors, and physiopathology of those wounds; additionally, we welcome research on existing strategies and emerging advanced clinical approaches to prevention and treatment management.

Prof. Dr. José Verdú-Soriano
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• epidemiology
• physiopathology
• advanced therapies
• hard-to-heal wounds
• chronic wounds
• skin ulcers
• new theoretical models
• etiology research
• risk factors
• prevention strategies

• Chronic Wounds or Hard to Heal Ulcers: Updating Epidemiology, Physiopathology, and Therapies in Journal of Clinical Medicine (7 articles)