Recent Progress in Rehabilitation Medicine—2nd Edition

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Rehabilitation".

Deadline for manuscript submissions: 31 August 2024 | Viewed by 3145

Special Issue Editor


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Guest Editor
1. Yamagata Prefectural University of Health Sciences, 260 Kamiyanagi, Yamagata 990-2212, Japan
2. Department of Internal Medicine and Rehabilitation Science, Tohoku University Graduate School of Medicine, Aoba-ku, Sendai, Japan
Interests: visceral impairment; comprehensive rehabilitation; exercise therapy; organ damage and protection; multi-organ connection
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Special Issue Information

Dear Colleagues,

I am pleased to invite you to contribute to this Special Issue entitled “Recent Progress in Rehabilitation Medicine—2nd Edition”. For more details on the first volume, in which we published more than 10 papers, please visit https://www.mdpi.com/journal/jcm/special_issues/Rehabilitation_Medicine.

With the aging of society worldwide, there are increasing numbers of people experiencing impairments and disabilities such as physical impairment, cognitive impairment, frailty and comorbidity. These are associated with an increased incidence of adverse healthcare outcomes, including hospitalization, poorer quality of life and increased healthcare expenditure. The number of people who need rehabilitation has increased dramatically.

Recent work in rehabilitation has made great progress. There are numerous randomized controlled studies in every field of rehabilitation. The outcome of rehabilitation, such as cardiac rehabilitation, is classified as Class I and Evidence A. Rehabilitation services are delivered quicker (stroke, etc.), more widely (heart failure, renal failure, pulmonary hypertension, etc.) and longer (not only in the acute and recovery stage, but also maintenance stage and before the surgery) in order to obtain better outcomes.

This second volume aims to focus on the recent advances in rehabilitation. Rehabilitation generally aims to "add life to years" by helping patients with impairments achieve and utilize their full physical, mental and social potential. However, growing evidence suggests that rehabilitation for patients with visceral impairment, such as renal, cardiac and pulmonary impairment, can not only improve exercise performance and the health-related quality of life, but also increase survival. Therefore, rehabilitation for patients does not simply aim to "add life to years" but “add life to years and years to life", which is a new rehabilitation concept.

We are soliciting such cutting-edge research reports and overviews in relation to clinical rehabilitation, to offer a promising model for the new field of rehabilitation.

Prof. Dr. Mashahiro Kohzuki
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • neuro-rehabilitation cognitive rehabilitation
  • spinal rehabilitation
  • orthopedic rehabilitation
  • pediatric rehabilitation
  • cancer rehabilitation
  • visceral rehabilitation
  • cardiac rehabilitation
  • pulmonary rehabilitation
  • renal rehabilitation
  • hepatic rehabilitation
  • rehabilitation for transplantation
  • fitness
  • peak VO2
  • multimorbidity and multiple disabilities (MMDs)
  • adding life to years and years to life

Published Papers (3 papers)

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17 pages, 2000 KiB  
Article
The Impact of a 6-Week Nordic Walking Training Cycle and a 14-Hour Intermittent Fasting on Disease Activity Markers and Serum Levels of Wnt Pathway-Associated Proteins in Patients with Multiple Myeloma
by Olga Czerwińska-Ledwig, Małgorzata Żychowska, Artur Jurczyszyn, Joanna Kryst, Jakub Deląg, Andżelika Borkowska, Joanna Reczkowicz, Tomasz Pałka, Przemysław Bujas and Anna Piotrowska
J. Clin. Med. 2024, 13(10), 2771; https://doi.org/10.3390/jcm13102771 - 8 May 2024
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Abstract
Background: Multiple myeloma (MM) accounts for about 10–15% of all diagnosed hematologic malignancies and about 1–2% of all cancer cases. Approximately 80–90% of MM patients develop bone disease and the changes rarely regress. It is only possible to stop or slow their [...] Read more.
Background: Multiple myeloma (MM) accounts for about 10–15% of all diagnosed hematologic malignancies and about 1–2% of all cancer cases. Approximately 80–90% of MM patients develop bone disease and the changes rarely regress. It is only possible to stop or slow their progression. A major role in bone destruction in MM is attributed to the Wnt signaling pathway, and its action can be modified by various types of interventions including training and diet. Therefore, the aim of this project was to evaluate the effects of a Nordic Walking (NW) training cycle and intermittent fasting (IF) on the levels of selected bone turnover markers associated with the Wnt pathway in patients with MM. Materials and methods: Results from 35 patients divided into training (NW and IF NW) and non-training (IF and control) groups were included in the analysis. A 6-week training cycle involving 60 min workouts 3 times a week was conducted. Body mass and composition as well as the levels of vitamin D, calcium and phosphorus, beta2-microglobulin, and albumin were examined before and after the completion of the training cycle. Markers of bone turnover were also determined: sclerostin (SOST), Dickkopf-related protein 1 (DKK-1), osteoprotegrin (OPG), osteopontin (OPN), and Tartrate-resistant acid phosphatase 5b (TRACP 5b). Results: There was no negative effect of IF or combined training and fasting on the nutritional status of the patients (the level of albumins was unchanged). Both training groups showed an increase in serum concentrations of the active metabolite of vitamin D (IF NW and NW: p = 0.001 and p = 0.022, respectively). The change in the concentration of this vitamin negatively correlated with the concentration of TRACP 5b (r = −0.413, p = 0.014). Evaluating the concentrations of markers related to bone turnover, a reduction in the concentrations of SOST (time: p = 0.026, time vs. group: p = 0.033) and TRACP 5b (time: p < 0.001, time vs. group p < 0.001) was indicated. Conclusions: The obtained results allow one to indicate the training with the poles as a safe and beneficial form of physical activity that should be recommended to patients suffering from MM. However, the results obtained in the present study are not sufficient to show the beneficial effect of IF applied without trainings. Full article
(This article belongs to the Special Issue Recent Progress in Rehabilitation Medicine—2nd Edition)
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13 pages, 1594 KiB  
Article
Long COVID Clinical Severity Types Based on Symptoms and Functional Disability: A Longitudinal Evaluation
by Manoj Sivan, Adam B. Smith, Thomas Osborne, Madeline Goodwin, Román Rocha Lawrence, Sareeta Baley, Paul Williams, Cassie Lee, Helen Davies, Kumaran Balasundaram and Darren C. Greenwood
J. Clin. Med. 2024, 13(7), 1908; https://doi.org/10.3390/jcm13071908 - 26 Mar 2024
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Abstract
Background: Long COVID (LC) is a multisystem clinical syndrome with functional disability and compromised overall health. Information on LC clinical severity types is emerging in cross-sectional studies. This study explored the pattern and consistency of long COVID (LC) clinical severity types over [...] Read more.
Background: Long COVID (LC) is a multisystem clinical syndrome with functional disability and compromised overall health. Information on LC clinical severity types is emerging in cross-sectional studies. This study explored the pattern and consistency of long COVID (LC) clinical severity types over time in a prospective sample. Methods: Participants with LC completed the condition-specific outcome measure C19-YRSm (Yorkshire Rehabilitation Scale modified version) at two assessment time points. A cluster analysis for clinical severity types was undertaken at both time points using the k-means partition method. Results: The study included cross-sectional data for 759 patients with a mean age of 46.8 years (SD = 12.7), 69.4% females, and a duration of symptoms of 360 days (IQR 217 to 703 days). The cluster analysis at first assessment revealed three distinct clinical severity type clusters: mild (n = 96), moderate (n = 422), and severe (n = 241). Longitudinal data on 356 patients revealed that the pattern of three clinical severity types remained consistent over time between the two assessments, with 51% of patients switching clinical severity types between the assessments. Conclusions: This study is the first of its kind to demonstrate that the pattern of three clinical severity types is consistent over time, with patients also switching between severity types, indicating the fluctuating nature of LC. Full article
(This article belongs to the Special Issue Recent Progress in Rehabilitation Medicine—2nd Edition)
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21 pages, 840 KiB  
Systematic Review
Assessing the Effectiveness of Rehabilitation Interventions through the World Health Organization Disability Assessment Schedule 2.0 on Disability—A Systematic Review
by Claudia-Gabriela Potcovaru, Teodor Salmen, Dragoș Bîgu, Miruna Ioana Săndulescu, Petruța Violeta Filip, Laura Sorina Diaconu, Corina Pop, Ileana Ciobanu, Delia Cinteză and Mihai Berteanu
J. Clin. Med. 2024, 13(5), 1252; https://doi.org/10.3390/jcm13051252 - 22 Feb 2024
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Abstract
(1) Background: The World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) is a tool designed to measure disability in accordance with the International Classification of Functioning, Disability and Health. Measuring disability is becoming increasingly important due to its high prevalence, which continues [...] Read more.
(1) Background: The World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) is a tool designed to measure disability in accordance with the International Classification of Functioning, Disability and Health. Measuring disability is becoming increasingly important due to its high prevalence, which continues to rise. Rehabilitation interventions can reduce disability and enhance functioning. (2) Objective: The present study aims to assess the impact of rehabilitation interventions on reducing disability, as measured by the WHODAS 2.0 questionnaire. It also seeks to identify which specific rehabilitation interventions are more effective and to explore other disability assessment questionnaires. (3) Methods: Following the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) methodology, we conducted a systematic review, with the protocol registered with the identifier CRD42023495309, focused on “WHODAS” and “rehabilitation” using PubMed and Web of Science electronic databases. (4) Results: We identified 18 articles from various regions encompassing patients with various health conditions, related to stroke, the cardiovascular system (cardiovascular disease, chronic heart failure), the pulmonary system (chronic obstructive pulmonary disease), the neurologic system (Parkinson’s disease, cerebral palsy, neurodegenerative disease), the musculoskeletal system (orthopaedic surgery), cancer, and chronic pain, and among frail elderly. These patients have received a wide range of rehabilitation interventions: from conventional therapy to virtual reality, robot-assisted arm training, exergaming, and telerehabilitation. (5) Discussion and Conclusions: A wide range of rehabilitation techniques can effectively improve disability with various comorbidities, offering numerous benefits. The WHODAS 2.0 questionnaire proves to be an efficient and reliable tool for measuring disability, and scores have a tendency to decrease after rehabilitation. Full article
(This article belongs to the Special Issue Recent Progress in Rehabilitation Medicine—2nd Edition)
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