New Insights into Contraception
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Obstetrics & Gynecology".
Deadline for manuscript submissions: closed (20 May 2022) | Viewed by 44782
Special Issue Editors
Interests: reproductive endocrinology; adenomyosis; contraception; endometriosis; placental pathophysiology.
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
After gaining front pages, even in the lay press, toward the end of the last millennium, contraception is now sort of taken for granted and is no longer a major topic. However, the estimated incidence of unintended pregnancies worldwide remains very high and, in this context, far from being nothing new to report, progress continues to be made toward methods specially designed for women with particular problems, be it because of their health or their living conditions, in order to improve both acceptance and continuation rate.
New estrogen–progestin oral combinations that contain the natural estrogen 17β-estradiol have been developed and marketed. New preparations utilizing another natural estrogen, estetrol (15α-hydroxy-estriol), are now under evaluation and will, hopefully, demonstrate better safety and tolerability, with special emphasis on lipid metabolism and effects on the hemostatic system. On the “minipill” front, a drospirenone-only preparation is at an advanced stage of development and there are indications that it may provide a better bleeding profile, with higher quality of life and adherence to this contraceptive method.
Research on vaginal contraception is currently exploring the consequences of the local administration of steroid hormones on the vaginal microbiome; new rings releasing the antiviral compound used in treating HIV, tenofovir, associated with levonorgestrel have been developed and are being tested. Meanwhile, in the area of intrauterine contraception, the recently developed three-dimensional, spherical, copper intrauterine device (IUD), seems to offer a significant reduction in the rates of perforation, malposition, and expulsion, while it can be inserted and removed in the same fashion as two-dimensional T-shaped IUDs.
The aim of this Special Issue is to highlight recent advances in meeting the needs of specific groups of women, especially those with contraindications to commonly used methods. We are happy to receive contributions in these fields.
Prof. Dr. Giuseppe Benagiano
Prof. Dr. Francesco Maria Primiero
Guest Editors
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Keywords
- Combined oral contraceptives
- Natural estrogens
- Progestin-only pills
- Drospirenone
- Contraceptive vaginal rings
- Intrauterine devices
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