Clinical Advances in Genetic Obesity and Health
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Endocrinology & Metabolism".
Deadline for manuscript submissions: 27 January 2025 | Viewed by 116
Special Issue Editors
Interests: childhood obesity; dietary patterns; food consumption; wine; mediterranean diet;noncommunicable diseases (NCDs)
Special Issues, Collections and Topics in MDPI journals
2. Department of Nutrition and Dietetics, School of Physical Education, Sports and Dietetics, University of Thessaly, 42132 Trikala, Greece
Interests: diet; nutrition; lifestyle; genetics; nutrigenetics; obesity; diabetes; metabolic syndrome; hypertension
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Weight gain and obesity are significant public health challenges with multifaceted origins, including genetic factors. Genetic predisposition plays a crucial role in adiposity, with most obesity cases attributed to polygenic etiology, where multiple genetic variants, typically single nucleotide polymorphisms (SNPs), collectively contribute to the obese phenotype. Moreover, the complexity of assessing the impact of multiple SNPs has led to the development of polygenic risk scores (PRS) to gauge not only the likelihood of developing obesity but to also assess an individual’s response to treatment. These variants often interact with environmental factors such as diet, physical activity, smoking, stress, mental health, overall lifestyle, and sociodemographic characteristics, influencing the onset and progression of adiposity.
This Special Issue aims to explore the latest clinical and research advancements in the field of genetic obesity as well as any obesity-related comorbidity, such as diabetes mellitus, cardiovascular disease, and metabolic syndrome. Unraveling the genetic component of obesity onset and progression will shed light on developing tailor-made and more effective treatment strategies.
The following Special Issue encourages the submission of original research articles and reviews that offer novel insights into i) the role of genetic variants in obesity diagnostics, ii) the role of genetic variants in the development of diagnostic tools for the early detection of genetic obesity, iii) the role of genetic variants in the evaluation of individuals’ response to clinical interventions (both pharmaceutical and lifestyle interventions), iv) the effect of gene–lifestyle interactions and their clinical implications, and v) the connection between pre-clinical findings and clinical solutions through translational research.
We look forward to receiving your contributions.
Prof. Dr. Rena Kosti
Dr. Ioanna Panagiota Kalafati
Guest Editors
Manuscript Submission Information
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Keywords
- obesity
- genetics
- health
- nutrigenetics
- clinical trials
- personalized
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