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Safety and Effectiveness of Medication in Elderly Patients
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Safety and Effectiveness of Medication in Elderly Patients

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Pharmacology".

Deadline for manuscript submissions: closed (31 May 2021) | Viewed by 2765

Special Issue Editor

Prof. Dr. Jens Søndergaard

E-Mail Website
Guest Editor
Research Unit for General Practice, Department of Public Health, University of Southern Denmark, Odense, Denmark
Interests: drug utilization; primary care

Special Issue Information

Dear Colleagues,

The elderly constitute a growing world population group, with more than 200 million people over 60 years of age. Elderly persons often suffer from multiple chronic conditions, and consequently polypharmacy is frequent. However, elderly persons are particularly susceptible to adverse drug events or interactions with other drugs due to their physiological changes, genetic predisposition, and environmental exposure. Consequently, integral and multidisciplinary approaches to promote and implement appropriate prescription and medication use in the elderly is warranted.

Prof. Dr. Jens Søndergaard
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • elderly
  • adverse effects
  • drug utilization
  • pharmacoepidemiology
  • physicians’ practice patterns

Published Papers (1 paper)

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Research

11 pages, 743 KiB  
Article
Patient- and Prescriber-Related Factors Associated with Potentially Inappropriate Medications and Drug–Drug Interactions in Older Adults
by Suhyun Jang, Sohyun Jeong and Sunmee Jang
J. Clin. Med. 2021, 10(11), 2305; https://doi.org/10.3390/jcm10112305 - 25 May 2021
Cited by 9 | Viewed by 2387
Abstract
We aimed to evaluate the prevalence of potentially inappropriate medication (PIM) use and drug–drug interactions (DDIs) in older adults and their associated factors. This cross-sectional study used National Health Insurance data of older adults in South Korea. The 2015 AGS Beers Criteria were [...] Read more.
We aimed to evaluate the prevalence of potentially inappropriate medication (PIM) use and drug–drug interactions (DDIs) in older adults and their associated factors. This cross-sectional study used National Health Insurance data of older adults in South Korea. The 2015 AGS Beers Criteria were used to classify PIM use and DDIs. The associations of PIM use and DDIs with patient- and prescriber-related factors were evaluated using multiple logistic regression. Of the older adults who received at least one outpatient prescription (N = 1,277,289), 73.0% and 13.3% received one or more prescriptions associated with PIM use or DDIs, respectively. Chlorphenamine was most commonly associated with PIM, followed by diazepam. Co-prescriptions of corticosteroids and NSAIDs accounted for 82.8% of DDIs. Polypharmacy and mainly visiting surgeons or neurologists/psychiatrists were associated with a higher likelihood of prescriptions associated with PIM use or DDIs. Older age, high continuity of care (COC), and mainly visiting a hospital were associated with a lower likelihood of PIM use or DDIs. Prescriptions associated with PIM use and DDIS were more frequent for low COC patients or those who mainly visited clinics; therefore, patients with these characteristics are preferred intervention targets for reducing prescriptions associated with PIM use and DDIs. Full article
(This article belongs to the Special Issue Safety and Effectiveness of Medication in Elderly Patients)
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