Clinical Applications of Metronomic Chemotherapy
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Oncology".
Deadline for manuscript submissions: closed (25 April 2022) | Viewed by 25617
Special Issue Editors
Interests: metronomic chemotherapy; pharmacokinetics; pharmacodynamics; clinical trials
Special Issues, Collections and Topics in MDPI journals
Interests: chemotherapy; cancer biology; metronomic chemotherapy; metastasis; immunotherapy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Metronomic chemotherapy has finally arrived in clinical use. After 20 years of preclinical development and clinical trials, the emerging data will be of paramount importance in allowing us to assess the impact of metronomic chemotherapy on different tumor types. Indeed, it is likely that the next decade will see a major reassessment of the possible applications of metronomic chemotherapy, alone and in combination with new therapeutic approaches such as immunotherapies, for the management of cancer. Moreover, the clinical trial results will likely profoundly affect the direction of the laboratory efforts that are going on in parallel, aimed at improving personalization of this therapeutic strategy. This Special Issue is our attempt to cover the past and present clinical results that have brought us to this pivotal moment and build the bases for future clinical developments. Scientists and clinicians caring for cancer patients are well aware of the challenges in dealing with this particular therapeutic approach, such as to obtain an improvement of patient survival without an important toxicity. The expectation today is that this different approach to clinical research on chemotherapy will translate into genuine progress in routine therapy. With this Special Issue, we hope to encourage submissions that discuss the current state-of-the-art, address ongoing knowledge gaps, and focus on ongoing controversies related to metronomic chemotherapy.
Dr. Guido Bocci
Prof. Giulio Francia
Guest Editors
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Keywords
- Metronomic chemotherapy
- Lymphoma
- Gastrointestinal cancers
- Breast cancer
- Lung cancer
- Prostate cancer
- Pediatric tumors
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