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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Pediatric Critical Care: Clinical Recognition, Management, and Outcomes

edited by Janet Hume

submission deadline 28 Feb 2025 | Viewed by 23 | Submission Open

Keywords: pediatric critical care medicine; sepsis; pediatric acute respiratory distress syndrome; mechanical ventilation; renal replacement therapy; chronic critical illness; post-intensive care syndrome

(This special issue belongs to the Section Clinical Pediatrics)

Updates in the Orthopedic Management of Foot Disorders: 2nd Edition

edited by

Carlo Biz

and

Pietro Ruggieri

submission deadline 28 Feb 2025 | Viewed by 21 | Submission Open

Keywords: foot pathologies; diabetic feet; forefoot deformities; oncology surgery; foot tumors; minimally invasive surgery; percutaneous surgery; foot joint arthroscopy; stress fractures

(This special issue belongs to the Section Orthopedics)

Physical Therapy in Musculoskeletal Disorders: Prevention, Diagnosis, Clinical Management and Treatment

edited by

Rubén Cuesta-Barriuso

submission deadline 28 Feb 2025 | Viewed by 20 | Submission Open

Keywords: physical therapy; musculoskeletal disorders; prevention; diagnosis; clinical management; treatment

(This special issue belongs to the Section Clinical Rehabilitation)

New Advances in Keratoplasty

edited by Cristina Bovone

submission deadline 28 Feb 2025 | Viewed by 17 | Submission Open

Keywords: lamellar keratoplasty; descemet stripping endothelial keratoplasty (DSAEK); descemet membrane endothelial keratoplasty (DMEK); deep anterior lamellar keratoplasty (DALK); keratoconus; corneal dystrophies; bullous keratopathy; anterior segment OCT

(This special issue belongs to the Section Ophthalmology)

Advanced Strategy for Diagnosis and Treatment of Obstructive Sleep Apnea Syndrome (OSAS)

edited by

Pierluigi Carratù

submission deadline 28 Feb 2025 | Viewed by 7 | Submission Open

Keywords: obstructive sleep apnea syndrome; diagnosis; obesity; treatment; CPAP; comorbidities; cardiovascular risk

(This special issue belongs to the Section Pulmonology)

Blood Disorders: Diagnosis, Management, and Future Opportunities

edited by

Cristina Panuzzo

and

Barbara Pergolizzi

submission deadline 28 Feb 2025 | Viewed by 6 | Submission Open

Keywords: blood disorders; biomarkers; personalized medicine; diagnosis; NGS; metabolomics; digital droplet PCR (ddPCR)

(This special issue belongs to the Section Hematology)

Cutting Edge of Minimally Invasive Spine Surgery

edited by

Yoshihisa Kotani

submission deadline 28 Feb 2025 | Viewed by 1 | Submission Open

Keywords: spine surgery; minimally invasive surgery; spinal deformity; spine fusion; enabling technology; spinal navigation; robotic surgery; spine materials; spinal endoscopy

(This special issue belongs to the Section Orthopedics)

Severe Infection and Antimicrobial Management in ICU

edited by Ming Chen

submission deadline 28 Feb 2025 | Viewed by 1 | Submission Open

Keywords: early diagnosis of bacteremia in ICUs; rational antibiotic treatment of bacteremia in ICUs; relationship between early diagnosis and antimicrobial management in ICUs

(This special issue belongs to the Section Infectious Diseases)

Clinical Progress of Mastectomy and Breast Reconstruction Surgery

edited by Antoine L. Carre and Mouchammed Agko

submission deadline 28 Feb 2025 | Submission Open

Keywords: autologous breast reconstruction; reinnervation; mastectomy; robotic DIEP (deep inferior epigastric perforator) flap; rib-sparing DIEP flap; neurotization of DIEP flap; nipple-sparing neurotization; nipple-sparing mastectomy of large breasts; hematoma after mastectomy; robotic mastectomy; pre-pectoral alloplastic reconstruction

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Research Trends and Applications of Hematopoietic Stem Cell Transplantation

edited by David C. Shyr and Robertson Parkman

submission deadline 28 Feb 2025 | Submission Open

Keywords: hematopoietic stem cell transplant; conditioning regimen; immunology; graft-versus-host disease; gene therapy; transplant-related toxicities; alternative donor stem cell transplant; supportive care

(This special issue belongs to the Section Hematology)

Orthopedic Surgery: Recent Advances and Prospects

edited by Mitchell K. Ng

submission deadline 28 Feb 2025 | Submission Open

Keywords: orthopedic surgery; clinical updates; joint reconstruction; spine surgery; trauma; elective surgery; peri-operative management

(This special issue belongs to the Section Orthopedics)

Emerging Technologies for Dental Imaging

edited by

Egon Burian

submission deadline 15 Mar 2025 | 2 articles | Viewed by 616 | Submission Open

Keywords: dental imaging; dental MRI; caries; periodontitis; orthodontics; oral surgery; craniomaxillofacial surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Cardiomyopathies: Current Treatment and Future Options: The Second Edition

edited by

Stefan Peters

submission deadline 15 Mar 2025 | Viewed by 28 | Submission Open

Keywords: hypertrophic cardiomyopathy; dilated cardiomyopathy; restrictive cardiomyopathy; amyloid cardiomyopathy; arrhythmogenic right ventricular cardiomyopathy; non-dilated left ventricular cardiomyopathy

(This special issue belongs to the Section Cardiology)

Corneal Diseases and Corneal Transplantation: Current Updates and Perspectives

edited by Itay Lavy,

Nir Erdinest

and Michael Mimouni

submission deadline 20 Mar 2025 | Submission Open

Keywords: corneal diseases; corneal transplantation; imaging techniques; pharmacological in-terventions; surgical interventions; tissue engineering

(This special issue belongs to the Section Ophthalmology)

Infective Endocarditis: What Is New in the Clinical Research: 2nd Edition

edited by

Petros Ioannou

submission deadline 25 Mar 2025 | Viewed by 49 | Submission Open

Keywords: infective endocarditis; vegetation; native valve; prosthetic valve; aortic valve; mitral valve; cardiac device; bloodstream infection; bacteremia

(This special issue belongs to the Section Cardiovascular Medicine)

New Perspectives in Liver Transplantation and Biliary Complications

edited by Marco Maria Pascale and Francesco Frongillo

submission deadline 28 Mar 2025 | Viewed by 24 | Submission Open

Keywords: liver transplant; cholangiopathy; ischemia/reperfusion injury; machine perfusion; extended-criteria donors

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Current Status of Endovascular Therapy for Acute Ischemic Stroke—2nd Edition

edited by

Iris Quasar Grunwald

submission deadline 30 Mar 2025 | Viewed by 7 | Submission Open

Keywords: endovascular therapy (EVT); cerebrovascular disease; thrombectomy; thrombolysis; ischemic stroke; interventional stroke therapy

(This special issue belongs to the Section Clinical Neurology)

Pediatric Obesity: Causes, Prevention and Treatment

edited by

Julie St-Pierre

submission deadline 31 Mar 2025 | Viewed by 427 | Submission Open

Keywords: 1000 first days of life; childhood obesity; lipids; healthy lifestyle; fetal programming

(This special issue belongs to the Section Endocrinology & Metabolism)

Interaction Between Systemic Diseases and Oral Diseases

edited by

Henk S. Brand

submission deadline 31 Mar 2025 | Viewed by 41 | Submission Open

Keywords: medical dental interaction; saliva; xerostomia; diagnostics; inflammatory bowel disease; cancer survivors; dental erosion; Sjö gren’ s disease; liver transplantation

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Urinary Tract Infection: Current Treatment and Future Options

edited by

Biagio Barone

submission deadline 31 Mar 2025 | Viewed by 35 | Submission Open

Keywords: urinary tract infections (UTIs); antibiotic resistance; probiotics and alternative therapies; diagnostic advancements; urinary infection management

(This special issue belongs to the Section Nephrology & Urology)

Presbyopia, Laser, Cataract and Refractive Surgery: State-of-the-Art Research

edited by

Ivo Guber

submission deadline 31 Mar 2025 | Viewed by 25 | Submission Open

Keywords: corneal grafts; cataract surgery; refractive surgery; presbyopia; laser; intraocular lenses

(This special issue belongs to the Section Ophthalmology)

Point of Care Sonography, An Essential Tool for Anesthesiology and Acute Care

edited by

Stefan U. Weber

and Se-Chan Kim

submission deadline 31 Mar 2025 | Viewed by 18 | Submission Open

Keywords: ultrasound; anesthesia; acute care; critical care; regional anesthesia; vascular access; lung ultrasound; echocardiography; gastric ultrasound; point of care

(This special issue belongs to the Section Anesthesiology)

State of the Art in Interventional Cardiology

edited by Antonios Karanasos

submission deadline 31 Mar 2025 | Viewed by 12 | Submission Open

Keywords: interventional cardiology; intravascular imaging; structural interventions; TAVI; vascular access; percutaneous coronary intervention; coronary stenting; cardiovascular diseases

(This special issue belongs to the Section Cardiology)

Hemodialysis: Clinical Updates and Advances

edited by

Gubensek Jakob

submission deadline 31 Mar 2025 | Viewed by 2 | Submission Open

Keywords: hemodiafiltration; medium cut-off membranes; expanded hemodialysis; vascular calcifications; renal anemia; vas-cular access; arterio-venous fistula; anticoagulation; outcomes

(This special issue belongs to the Section Nephrology & Urology)

Cutting-Edge Advances in Assisted Reproductive Technologies (ART) and In Vitro Fertilization (IVF)

edited by Itai Gat

submission deadline 31 Mar 2025 | Viewed by 2 | Submission Open

Keywords: assisted reproductive technologies (ART); in vitro fertilization (IVF); artificial intelligence; genetics and epigenetics; fertility preservation; male factor

(This special issue belongs to the Section Reproductive Medicine & Andrology)

Chronic Kidney Disease: Clinical Challenges and Management

edited by

Shuzo Kobayashi

and

Takayasu Ohtake

submission deadline 31 Mar 2025 | Viewed by 1 | Submission Open

Keywords: chronic kidney disease; clinical trial; end-stage renal disease; kidney dysfunction; management; challenge

(This special issue belongs to the Section Nephrology & Urology)

Trends and Innovations in Regenerative Medicine and Non-surgical Aesthetics

edited by

Eqram Rahman

, William R. Webb, Jean D.A. Carruthers and Afshin Mosahebi

submission deadline 20 Apr 2025 | Viewed by 63 | Submission Open

Keywords: regenerative medicine; non-surgical aesthetics; stem cell therapy; ATMPs; skin rejuvenation; anti-aging treatments; growth factors; bioactive molecules; botulinum toxin A; dermal fillers; energy devices; AI in aesthetics; patient satisfaction; safety and efficacy; regulatory considerations

(This special issue belongs to the Section Epidemiology & Public Health)

One Size Does Not Fit All: New Strategies to Improve Overall Health and Physical Activity Behavior in Vulnerable Populations

edited by

Gabriel Dias Rodrigues

and

Marco Vicenzi

submission deadline 30 Apr 2025 | 4 articles | Viewed by 4117 | Submission Open

Keywords: chronic diseases; vascular function; aging; sedentarism; active breaks; exercise; respiratory muscle training; hostile environments

(This special issue belongs to the Section Sports Medicine)

Advancements in Venous Thrombosis Management: From Prevention to Long-Term Care

edited by

Luca Costanzo

submission deadline 30 Apr 2025 | Viewed by 40 | Submission Open

Keywords: venous thromboembolism; post-thrombotic syndrome; direct oral anticoagulant; pulmonary embolism; thrombosis; factor xia inhibitors; thrombolysis; cancer; antiphospholipid syndrome; catheter-directed thrombolysis; inferior vena cava filters

(This special issue belongs to the Section Vascular Medicine)

Challenges and Opportunities in Geriatric Nephrology and Urology

edited by Giulio Romano

submission deadline 20 May 2025 | Viewed by 61 | Submission Open

Keywords: kidney disease; elderly patient; epidemiology; pharmacological therapy; lifestyle diet

(This special issue belongs to the Section Nephrology & Urology)

Latest Research on Male Infertility

edited by

Manesh Kumar Panner Selvam

submission deadline 31 May 2025 | Viewed by 49 | Submission Open

Keywords: testis; sperm; seminal plasma; spermatogenesis; fertilization; omics; proteomics; oxidative stress; sperm DNA fragmentation; varicocele; male infertility; testicular cancer; infertility management; ART

(This special issue belongs to the Section Reproductive Medicine & Andrology)

Unruptured Intracranial Aneurysms: From Diagnosis to Treatment

edited by