Biomaterials for Drug Release and Tissue Engineering

A special issue of Journal of Functional Biomaterials (ISSN 2079-4983). This special issue belongs to the section "Biomaterials for Drug Delivery".

Deadline for manuscript submissions: closed (31 May 2023) | Viewed by 3134

Special Issue Editors


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Guest Editor
School of Medicine and Health, Harbin Institute of Technology, Yikuang Street 2, Building 2H Room 406, Harbin 150080, China
Interests: STENT; drug delivery; drug encapsulation; drug release; biomedical materials; implants; thin films; lamination; layer by layer; ellipsometry
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Guest Editor
Skolkovo Innovation Center, Skolkovo Institute of Science and Technology, 3 Nobel Str., 143005 Moscow, Russia
Interests: biomedical materials; physiology; drug encapsulation; drug release; drug delivery; coatings; lamination; ultrasound; thin films; tissue engineering; cell proliferation

Special Issue Information

Dear Colleagues,

Biomaterials are a class of materials classified by their biologically benign properties. For this reason, they are often utilized as materials or coatings for implants such as STENTs or other biomedical devices. Due to the wide variety of biomaterials, which range from titanium to polymers such as polylactic acid, the applications differ vastly. Hydrophobic biomaterials such as polylactic acid are utilized for drug encapsulation, as well as self-removing implants, while metallic biomaterials are often utilized as frameworks. For this Special Issue, we invite manuscripts which encompass a wide range of biomaterial topics, including (but not limited to):

  • Clinical utilization of biomaterials;
  • Antibacterial properties of biomaterials;
  • STENTs;
  • Cell colonization and proliferation on biomaterials;
  • Drug encapsulation, delivery and release within biomaterials;
  • Biocompatibility;
  • Implants;
  • Biomaterials as diagnostic tools, contrast agents, imaging;
  • Clinical trials and case reports of biomaterials.

We look forward to your valuable contributions.

Prof. Dr. Johannes Frueh
Dr. Olga A. Sindeeva
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Functional Biomaterials is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • self-medicating implants
  • drug encapsulation
  • cell proliferation on surfaces
  • biomaterials
  • drug encapsulation
  • drug release
  • drug delivery

Published Papers (1 paper)

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Research

22 pages, 15639 KiB  
Article
Surface Modification of Additively Fabricated Titanium-Based Implants by Means of Bioactive Micro-Arc Oxidation Coatings for Bone Replacement
by Anna I. Kozelskaya, Sven Rutkowski, Johannes Frueh, Aleksey S. Gogolev, Sergei G. Chistyakov, Sergey V. Gnedenkov, Sergey L. Sinebryukhov, Andreas Frueh, Vladimir S. Egorkin, Evgeny L. Choynzonov, Mikhail Buldakov, Denis E. Kulbakin, Evgeny N. Bolbasov, Anton P. Gryaznov, Ksenia N. Verzunova, Margarita D. Apostolova and Sergei I. Tverdokhlebov
J. Funct. Biomater. 2022, 13(4), 285; https://doi.org/10.3390/jfb13040285 - 8 Dec 2022
Cited by 20 | Viewed by 2713
Abstract
In this work, the micro-arc oxidation method is used to fabricate surface-modified complex-structured titanium implant coatings to improve biocompatibility. Depending on the utilized electrolyte solution and micro-arc oxidation process parameters, three different types of coatings (one of them—oxide, another two—calcium phosphates) were obtained, [...] Read more.
In this work, the micro-arc oxidation method is used to fabricate surface-modified complex-structured titanium implant coatings to improve biocompatibility. Depending on the utilized electrolyte solution and micro-arc oxidation process parameters, three different types of coatings (one of them—oxide, another two—calcium phosphates) were obtained, differing in their coating thickness, crystallite phase composition and, thus, with a significantly different biocompatibility. An analytical approach based on X-ray computed tomography utilizing software-aided coating recognition is employed in this work to reveal their structural uniformity. Electrochemical studies prove that the coatings exhibit varying levels of corrosion protection. In vitro and in vivo experiments of the three different micro-arc oxidation coatings prove high biocompatibility towards adult stem cells (investigation of cell adhesion, proliferation and osteogenic differentiation), as well as in vivo biocompatibility (including histological analysis). These results demonstrate superior biological properties compared to unmodified titanium surfaces. The ratio of calcium and phosphorus in coatings, as well as their phase composition, have a great influence on the biological response of the coatings. Full article
(This article belongs to the Special Issue Biomaterials for Drug Release and Tissue Engineering)
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