Diabetes and Its Complications: From Research to Clinical Practice

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Clinical Medicine, Cell, and Organism Physiology".

Deadline for manuscript submissions: 20 July 2025 | Viewed by 1068

Special Issue Editors


E-Mail Website
Guest Editor
Research Administration Center, Saitama Medical University, Saitama 350-0495, Japan
Interests: type 2 diabetes mellitus; diabetes medications; chronic kidney disease; heart failure; hypertension; liver disease; obesity; aging

E-Mail Website
Guest Editor
Research Administration Center, Saitama Medical University, Saitama 350-0495, Japan
Interests: heart failure; cardiorenal syndrome; diabetes; organ protection; renin–angiotensin system; induced pluripotent stem cell

Special Issue Information

Dear Colleagues,

Diabetes is a complex and progressive disease, accompanied by numerous complications that manifest over time. The most common impact is on the eyes, nerves, heart, blood vessels, kidneys, and liver. Conventional diabetes medications have been able to prevent and delay the progression of diabetic microvascular complications by managing blood glucose levels but prove limited in addressing complications stemming from macrovascular damage.

This Special Issue focuses on the latest research and clinical evidence concerning complications such as cardiovascular diseases; including myocardial infarction and heart failure; renal complications, like diabetic nephropathy; and complications associated with chronic diabetes-related liver metabolic diseases, such as MASLD. Additionally, it delves deeply into the intricate relationship between the risks of these complications and factors such as obesity and aging.

Additionally, emerging treatment approaches for these complications, particularly novel diabetes medications like GLP-1 receptor agonists and SGLT2 inhibitors, exhibit promising effectiveness. Recent discoveries, grounded in robust evidence, signify a transformative shift in diabetes management, fostering the exploration of more holistic and efficacious strategies.

In conclusion, this Special Issue serves as a pivotal resource, providing current insights into the dynamic interplay of diabetes, its complications, and related factors. It advances our understanding of its disease mechanisms and provides clinicians with the relevant information for informed decision making in diabetes management.

Dr. Makoto Katoh
Prof. Dr. Takaaki Senbonmatsu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • diabetes
  • cardiovascular diseases
  • kidney disorders
  • liver diseases
  • obesity
  • aging
  • diabetes medications

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Review

24 pages, 2611 KiB  
Review
Advancing the Diagnosis of Diabetic Neuropathies: Electrodiagnostic and Skin Autofluorescence Methods
by Dan Trofin, Bianca-Margareta Salmen, Teodor Salmen, Daniela Marilena Trofin and Delia Reurean-Pintilei
J. Pers. Med. 2024, 14(8), 884; https://doi.org/10.3390/jpm14080884 - 21 Aug 2024
Cited by 1 | Viewed by 778
Abstract
Introduction: Diabetic neuropathy (DN) is a generic term for various neuropathies coexisting in a single patient. Clinical diagnosis alone can be misleading, yet routine electrodiagnostic studies in diabetes care are rare. Skin autofluorescence (SAF) is a recognized DN risk factor with potential screening [...] Read more.
Introduction: Diabetic neuropathy (DN) is a generic term for various neuropathies coexisting in a single patient. Clinical diagnosis alone can be misleading, yet routine electrodiagnostic studies in diabetes care are rare. Skin autofluorescence (SAF) is a recognized DN risk factor with potential screening value. This article highlights the diagnostic challenges and raises awareness of the often underdiagnosed neuropathic conditions in diabetes patients. Material and Methods: We present common entrapment neuropathy cases from our diabetes clinic’s electrodiagnosis laboratory in Iași, Romania. We selected seven type 2 diabetes patients with sensory or sensory-motor distal polyneuropathy and atypical DN presentations investigated through electroneurography (ENG) and electromyography (EMG) with the Neurosoft® EMG instrument and SAF measured by standard procedures. Subsequently, a narrative literature review was conducted. Results: Entrapment neuropathies were diagnosed in all the patients: three carpal tunnel syndromes, two ulnar neuropathies (one proximal, one distal), one peroneal neuropathy, and one case of meralgia paresthetica. The lower-limb cases showed radiculoplexopathy, and there was one case of superficial radial nerve neuropathy. The SAF values ranged from 2.5 AU to 3.4 AU. Conclusions: Electrodiagnosis is essential for detecting focal neuropathies in patients with sensory-motor distal polyneuropathy. Elevated SAF levels may correlate with symptom severity, although further research, including large cohorts, is needed. Full article
(This article belongs to the Special Issue Diabetes and Its Complications: From Research to Clinical Practice)
Show Figures

Figure 1

Back to TopTop