The Molecular Targeting of Glioblastoma: Drug Discovery and Therapies

Dear Colleagues,

Among the most lethal cancer types, glioblastoma still holds a prominent position and represents a tremendous challenge for physicians, patients and scientists. A number of therapeutic strategies have been developed, but results, in terms of life expectancy, are far from the desired objectives. For this reason, the research for new molecular targets is increasingly pressing. Gene amplification, mutation and methylation represent research fields in glioblastoma that continuously provide new perspectives for therapy. Additionally, molecular targeting by integrin receptors has, in recent years, given rise to new hopes. This Special Issue of the Journal of Personalized Medicine aims to cover the current most advanced therapies, with a particular focus on the discovery of new potential molecular targets and related forthcoming therapies. Special attention will be devoted to the experimental models currently used in drug discovery and to their potential application in glioblastoma research. The overall purpose of this Special Issue is to share the knowledge of different research fields and provide researchers and clinicians with new insights in order to fight this mortal enemy successfully.

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