Novel Principles and Methods in Bacterial Cell Cycle Physiology: Celebrating the Charles E. Helmstetter Prize in 2022
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Biochemistry, Biophysics and Computational Biology".
Deadline for manuscript submissions: closed (30 April 2023) | Viewed by 19788
Special Issue Editors
Interests: integrative approaches to the bacterial cell cycle, origins of life; biotechnology; systems biology
Special Issue Information
Dear Colleagues,
Understanding the bacterial cell cycle is fundamental to understanding the physiology of the cell and, hence, to all the fields that depend on microbial physiology, such as clinical microbiology, industrial biotechnology, the origins of life, xenobiology, environmental microbiology, and synthetic biology.
Charles E. Helmstetter is widely acknowledged as the person who provided the experimental and theoretical bases for our understanding of the bacterial cell cycle. Indeed, the ensemble of his ingenious investigations, designed and performed by himself from the 1960s to the end of the century, is considered to have defined the field, which is exceptional in science.
A group of specialists in this field collaborated to create The Charles E Helmstetter Prize for Groundbreaking Research in Bacterial Cell Cycle Physiology. The Prize will be awarded every two years. The aim of the present Special Issue is to celebrate the The Charles E Helmstetter Prize in 2022. The first three recipients have been selected and will be awarded the Prize in the opening session of the EMBO Workshop “Bacterial cell biophysics: DNA replication, growth, division, size and shape” https://meetings.embo.org/event/22-bacteria-biophysics, to be held in Israel, 11–15 December 2022.
The first session of this workshop (entitled "Bacterial Physiology Comes of Age at 60") will be devoted to the Prize, to the achievements of Dr. Helmstetter and the three laureates, and to the implications stemming from their pioneering investigations. A number of scientists in the field, selected for their relationships to Helmstetter and his work, have been invited to contribute chapters; other colleagues are also welcome to submit relevant chapters.
Prof. Dr. Vic Norris
Prof. Dr. Arieh Zaritsky
Guest Editors
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Keywords
- synchrony for bacterial cell cycle
- DNA replication and I-BCD periods
- cell dimensions, orisome, replisome and divisome
- overlapping rounds of replication
- nucleoid structure and membrane domains
- cell variability and individuality
- thymine limitation, unbalanced growth, and thymine-less death
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