Erectile Dysfunction and Sexual Health: Current Trends in Evaluation and Treatment

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Urology & Nephrology".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 1103

Special Issue Editors


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Guest Editor
Department of Urology, “Iuliu Hatieganu” University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania
Interests: urologic oncology; robotic-assisted surgery; laparoscopic surgery; urothelial cancer; prostate cancer
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Guest Editor
Department of Urology, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania
Interests: urothelial cancer; oncological surgery; erectile dysfunction

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Guest Editor Assistant
Department of Urology, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș, 540139 Târgu Mureș, Romania
Interests: erectile dysfunction; urosepsis; complicated urinary tract infections; multiple drug-resistant bacteria; oncology; lithiasis

Special Issue Information

Dear Colleagues,

Erectile dysfunction and sexual health are fundamental aspects of men’s overall well-being, yet they remain underdiagnosed and undertreated concerns. Historically, discussions about sexual function were often limited to psychosocial or relational dimensions. However, in recent decades, major advances in our understanding of the physiological, hormonal, and neurovascular mechanisms of erectile function have transformed the field into a multidisciplinary and clinically dynamic specialty.

This Special Issue aims to provide a comprehensive and up-to-date overview of current concepts, diagnostic tools, and treatment strategies in erectile dysfunction and male sexual health.

We welcome original research and review articles that explore the complex etiology of ED—including vascular, neurogenic, endocrinologic, iatrogenic, and psychogenic factors—and its associations with chronic conditions such as diabetes, cardiovascular disease, metabolic syndrome, and depression.

The scope also includes research on ejaculatory and orgasmic disorders, penile rehabilitation, and the sexual health of men undergoing cancer treatment or gender-affirming care.

We particularly encourage submissions that highlight novel and cutting-edge approaches, such as regenerative medicine, stem cell therapy, low-intensity shockwave therapy, penile implants, neuroimaging, wearable technology, telemedicine applications, and sexual counseling models.

Papers focusing on personalized medicine, patient-centered outcomes, quality of life, and long-term management are also of great interest.

We invite urologists, andrologists, endocrinologists, sexologists, psychologists, and researchers from related disciplines to contribute high-quality manuscripts that will enrich our understanding and improve patient care in this essential domain of health.

Dr. Bogdan Petrut
Dr. Bogdan Ovidiu Feciche
Prof. Dr. Nicolae Crisan
Guest Editors

Dr. Daniel Porav-Hodade
Guest Editor Assistant

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Keywords

  • erectile dysfunction
  • ejaculatory and orgasmic disorders
  • vascular
  • neurogenic
  • endocrinologic
  • iatrogenic
  • psychogenic

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Published Papers (1 paper)

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Research

15 pages, 1099 KB  
Article
The Relationship Between Erectile Dysfunction and Dyadic Adjustment, Couple Relationship Quality, and Intimacy: A Cross-Sectional Study
by Dragoș-Mihail Trifu, Daniel-Corneliu Leucuța, Martina-Luciana Pintea-Trifu, Florin Elec, Nicolae Crișan, Dan Eniu and Ioan Coman
Medicina 2025, 61(9), 1590; https://doi.org/10.3390/medicina61091590 - 3 Sep 2025
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Abstract
Background and Objectives: This study aimed to evaluate the association between relationship dynamics as measured by dyadic adjustment and factors such as erectile function and lower urinary tract symptoms, adjusting for relevant clinical characteristics. Materials and Methods: This cross-sectional study collected [...] Read more.
Background and Objectives: This study aimed to evaluate the association between relationship dynamics as measured by dyadic adjustment and factors such as erectile function and lower urinary tract symptoms, adjusting for relevant clinical characteristics. Materials and Methods: This cross-sectional study collected data from 94 males in relationships of at least 6 months and with a prostate volume equal to or higher than 30 cc. Lower urinary tract symptoms, erectile function, and relationship dynamics were assessed with the International Prostate Symptom Score (I-PSS), International Index of Erectile Function (IIEF), Dyadic Adjustment Scale (DAS). Results: We found significant positive correlations between DAS affective expressions (AEs) and erectile dysfunction duration; between IIEF general satisfaction and DAS dyadic adjustment (DA), dyadic consensus (DC), and dyadic cohesion (DH); and between prostate width and DAS DA and DC (all ρ ≈ 0.2–0.3, p < 0.05). Further multiple regression analyses adjusting for age, prostate width, and comorbidities showed that the associations between IIEF general satisfaction and DAS DA (p = 0.013) and DH (p = 0.008) remained significant, while the relationship with DAS DC (p = 0.051) was borderline. Conclusions: Our findings highlight that general sexual satisfaction, as measured with the IIEF, had a small but independent association with higher affective expressions, dyadic cohesion, and dyadic consensus in couples, which are key domains of dyadic adjustment, regardless of relationship duration, prostate width, and comorbidities. These results emphasize the importance of considering sexual satisfaction in the context of relationship quality and, therefore, involving the female partner in the assessment and treatment of erectile dysfunction. Full article
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