Updates on Plastic and Reconstructive Surgery: Current Management of Skin Cancer
A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Dermatology".
Deadline for manuscript submissions: 31 December 2024 | Viewed by 643
Special Issue Editor
Interests: skin cancer; microsurgery; cancer immunology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Recently, the prevalence of skin cancer has increased due to environmental problems and the aging population; people's interest in this condition is also increasing. Skin cancer is characterized as the out-of-control growth of abnormal cells in the epidermis, the outermost skin layer, caused by unrepaired DNA damage that triggers mutations. These mutations cause the skin cells to multiply rapidly and form malignant tumors. The main types of skin cancer are basal cell carcinoma (BCC), squamous cell carcinoma (SCC), melanoma, and Merkel cell carcinoma (MCC). For skin cancer management, obtaining an accurate diagnosis is the most important initial step. We typically conduct a punch biopsy to take a deep sample of the skin and obtain an initial opinion from the pathologist. There are many diagnostic imaging tools that are available for skin cancer management, e.g., ultrasound, computed tomography, magnetic resonance imaging, positron emission tomography, etc. After this imaging, we get to know the boundary and depth of the malignancy. Surgery is a common way to address skin cancer, and in some cases, it may be the only treatment needed.
Skin cancer has a very wide spectrum compared to other types of malignancies. First, histologic cell types are as diverse as basal cells, squamous cells, melanocytes, fibrocytes, myocytes, glandular epithelium, etc. In many solid organ tumors, a few cell types are predominant. Second, skin cancer can occur anywhere in our body. Skin is the largest organ; skin cancer can occur in the scalp, face, upper and lower extremities, hand and foot, chest and abdomen, back, and buttocks. Third, there are too many reconstructive options. After skin cancer ablation, we have to choose the most ideal reconstructive method. It includes the primary closure, skin graft, local flap, free flap, etc. Each method has its own advantages and disadvantages. The operator has their own opinion and individual experiences. In addition to surgical treatment for skin cancer, cancer immunotherapy is a field that has recently received a lot of attention.
The purpose of this Special Issue is to discuss matters associated with skin cancer and its management. From histology and imaging studies to Definity surgery, each step has its own debate and unsolved problems. The scope of this Special Issue is deliberately broad to encourage the coverage of a wide range of topics and perspectives related to the management of skin cancer. This includes not only surgical treatments but also pathology, immunology, epidemiology, diagnosis, and the latest cutting-edge immunotherapy.
Dr. Seokchan Eun
Guest Editor
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Keywords
- melanoma
- squamous cell carcinoma
- basal cell carcinoma
- dermatofibrosarcoma protuberans
- Merkel cell cancer
- punch biopsy
- imaging study
- sentinel lymph node biopsy
- lymph node dissection
- surgical safety margin
- Mohs surgery
- free flap
- local flap
- skin graft
- immunotherapy
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