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Medicina
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Advances in the Diagnosis and Treatment of Type 2 Diabetes...
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Advances in the Diagnosis and Treatment of Type 2 Diabetes Mellitus

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Endocrinology".

Deadline for manuscript submissions: 30 December 2025 | Viewed by 1783

Special Issue Editors

Prof. Dr. Bogdan Timar

E-Mail Website
Guest Editor
1. Department VII Internal Medicine—Diabetes, Nutrition, Metabolic Diseases, and Systemic Rheumatology, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania
2. Centre of Molecular Research in Nephrology and Vascular Disease, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania
3. Diabetes, Nutrition, and Metabolic Diseases, “Pius Brinzeu” Emergency Hospital, Timisoara, Romania
Interests: glycemic variability; continuous glucose monitoring; diabetes technology; diabetic neuropathy; cardiac neuropathy
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Romulus Timar

E-Mail Website
Guest Editor
1. Department VII Internal Medicine—Diabetes, Nutrition, Metabolic Diseases, and Systemic Rheumatology, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania
2. Centre of Molecular Research in Nephrology and Vascular Disease, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania
3. Diabetes, Nutrition, and Metabolic Diseases, “Pius Brinzeu” Emergency Hospital, Timisoara, Romania
Interests: heart failure; time in range; time in tight range; liposome; monoclonal antibodies; Lp a; MASH
Dr. Adina Braha

E-Mail Website
Guest Editor Assistant
1. Department of Second Internal Medicine—Diabetes, Nutrition, Metabolic Diseases, and Systemic Rheumatology, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, Romania
2. Department of Diabetes, Nutrition and Metabolic Diseases Clinic, Pius Brînzeu” Emergency Clinical County University Hospital, 300723 Timisoara, Romania
Interests: bariatric surgery; nutritional interventions; chronic kidney disease

Special Issue Information

Dear Colleagues,

The landscape of type 2 diabetes diagnosis is evolving rapidly with the advancements in technology and methodologies aimed at improving patient outcomes through more accurate and user-friendly monitoring solutions. These innovations not only enhance disease management but also hold promise for earlier detection and intervention.

This Special Issue aims to present the latest research findings in type 2 diabetes. Authors are encouraged to submit review/systematic reviews, meta-analysis papers, or original research articles focusing on new diagnostic markers for type 2 diabetes and its complications, nanotechnology as a tool for early diagnosis, continuous glucose monitoring, new drug classes, bariatric surgery, and gut–brain axis approaches for managing type 2 diabetes.

Prof. Dr. Bogdan Timar
Prof. Dr. Romulus Timar 
Guest Editors

Dr. Adina Braha
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • novel diagnostic markers of type 2 diabetes and its complications
  • continuous glucose monitoring in type 2 diabetes
  • time in tight range in type 2 diabetes
  • nanotechnology in type 2 diabetes
  • SGLT-2 inhibitors
  • GLP-1 receptor agonists, dual GIP/GLP-1 receptor agonists
  • next-generation GLP-1/GIP/glucagon triple agonists
  • amylin analogues
  • bariatric surgery in managing type 2 diabetes and obesity
  • gut microbiota in type 2 diabetes
  • liposome
  • monoclonal antibodies
  • Lp a
  • MASH in type 2 diabetes
  • differentiated thyroid cancer and pancreatic cancer in type 2 diabetes mellitus

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

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Research

8 pages, 277 KiB  
Article
Safety of SGLT2 Inhibitors and Urinary Tract Infections in Clinical Practice—A Cross-Sectional Study
by Liana Iordan, Vlad Florian Avram, Bogdan Timar, Adrian Sturza, Simona Popescu, Oana Albai and Romulus Zorin Timar
Medicina 2024, 60(12), 1974; https://doi.org/10.3390/medicina60121974 - 1 Dec 2024
Viewed by 1270
Abstract
Background and Objectives: Type 2 diabetes (T2DM) affects millions across the globe, generating a veritable public health issue through quality-of-life-reducing chronic complications, among which urinary tract infections are the most common. A shift in the disease managing paradigm from a glucose-centered view [...] Read more.
Background and Objectives: Type 2 diabetes (T2DM) affects millions across the globe, generating a veritable public health issue through quality-of-life-reducing chronic complications, among which urinary tract infections are the most common. A shift in the disease managing paradigm from a glucose-centered view to a concept of cardio-reno-metabolic health has uniquely placed SGLT2 inhibitors as viable medication for the complex management of T2DM and its comorbidities. Some concerns have been raised over the increased likelihood of urinary tract infections (UTIs) associated with SGLT2 inhibitor use. The current study aims to evaluate the risk of developing urinary tract infections if patients with type 2 diabetes take SGLT2 inhibitors and determine those factors which make these patients more prone to develop this undesired complication. Materials and Methods: A cross-sectional, noninterventional evaluation of 328 patients with type 2 diabetes consecutively admitted to the Diabetes Clinic of “Pius Brinzeu” County Emergency Hospital in Timisoara, between January and February of 2024, was performed by examining medical charts and running statistical analyses using MedCalc version 22.26.0.0. Results: There was no statistical difference between patients taking SGLT2 inhibitors and those taking other glucose lowering medications when examining the presence of UTIs. Those patients with a higher HbA1c or BMI showed an increased predisposition to contracting UTI. The female gender was also associated with an increased likelihood of UTI. A further evaluation of the sublot of patients taking SGLT2 inhibitors revealed that not only higher BMI or HbA1c could be a predictor for the likelihood of developing UTI, but also a longer duration of T2DM was a predisposing factor. Conclusions: The use of SGLT2 inhibitors did not increase the likelihood of developing a urinary tract infection in this patient population. Full article
(This article belongs to the Special Issue Advances in the Diagnosis and Treatment of Type 2 Diabetes Mellitus)
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