Recent Breakthroughs in the Diagnosis and Treatment of Oral Inflammatory Diseases

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Dentistry and Oral Health".

Deadline for manuscript submissions: 28 February 2025 | Viewed by 954

Special Issue Editors


E-Mail Website
Guest Editor
Department of Dermatovenereology, University Hospital Center Sestre Milosrdnice, School of Dental Medicine, University of Zagreb, 10000 Zagreb, Croatia
Interests: allergy; inflammation; psychoneuroimmunology; dermatovenerology; microbiome
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor Assistant
Department of Oral Medicine, School of Medicine (Study of Dental Medicine), University of Split, Split, Croatia
Interests: oral candidiasis; burning mouth syndrome; oral lichen plnaus; oral cancer; saliva

Special Issue Information

Dear Colleagues,

Oral inflammatory diseases with different aetiopathogenetic mechanisms can occur as a primary disease, as a consequence of systemic diseases, or iatrogenically (e.g., oncological therapy). A detailed medical and dental history and a clinical oral examination are the basis for correct and timely diagnosis and treatment.

The treatment of patients with oral inflammatory diseases should be multidisciplinary (involving specialists in dermatoveneology, immunology, gastroenterology, and oncology). The evidence-based connection between oral and general health is well known. The connection between physical and mental health in the treatment of oral inflammatory diseases should not be neglected either.

The aim of this Special Issue of Medicina is to present the latest findings and achievements in the diagnosis and treatment of oral inflammatory diseases, including the aetiopathogenetic mechanism, clinical picture, diagnosis, treatment, and clinical outcomes. In addition, contributing articles relate to all multidisciplinary fields (medicine and dentistry) in which the oral cavity is affected by inflammation.

We invite colleagues from all over the world to publish their latest clinical and scientific experiences in this Special Issue, “Recent Breakthroughs in the Diagnosis and Treatment of Oral Inflammatory Diseases”, in the form of original studies, case series, case–control studies, randomised control trials, systematic reviews, and meta-analyses. New insights in the treatment of oral inflammatory diseases (with a multidisciplinary approach) are crucial for achieving optimal clinical outcomes and thus for general health.

Dr. Liborija Lugović-Mihić
Guest Editor

Dr. Ana Glavina
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • oral inflammatory diseases
  • multidisciplinary
  • clinical manifestation
  • diagnosis
  • treatment
  • clinical outcome

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

12 pages, 584 KiB  
Article
Evaluation of the Hypothalamic–Pituitary–Adrenal Axis in Patients with Primary Sjögren’s Disease
by Ana Glavina, Petar Zurak, Dinko Martinović, Majda Gotovac, Daniela Šupe-Domić and Liborija Lugović-Mihić
Medicina 2024, 60(11), 1886; https://doi.org/10.3390/medicina60111886 - 17 Nov 2024
Viewed by 622
Abstract
Background and Objectives: Patients with primary Sjögren’s disease (pSjD) show contradictory results regarding the activity of the hypothalamic–pituitary–adrenal (HPA) axis. The aim of this study was to determine the salivary cortisol concentration to evaluate the function of the HPA axis (hypoactive/hyperactive) between patients [...] Read more.
Background and Objectives: Patients with primary Sjögren’s disease (pSjD) show contradictory results regarding the activity of the hypothalamic–pituitary–adrenal (HPA) axis. The aim of this study was to determine the salivary cortisol concentration to evaluate the function of the HPA axis (hypoactive/hyperactive) between patients with pSjD and control subjects. Materials and Methods: A total of 34 subjects participated in the cross-sectional study: 17 patients with pSjD and 17 control subjects. Stimulated whole saliva (SWS) was used to determine salivary cortisol concentration using an enzyme-linked immunosorbent assay (ELISA). Results: The salivary cortisol concentration showed a statistically significant difference between patients with pSjD and control subjects (4.69 ± 2.88 vs. 0.49 ± 0.37; p < 0.001; Student t-test). The area under the curve (AUC) was 100.0% in patients with pSjD (p < 0.001). The cut-off point was set to >1.454. The patients with pSjD had four times higher scores for depression and stress and six times higher scores for anxiety compared to the control subjects (p = 0.048, p < 0.001, p = 0.038; Mann–Whitney U test). The patients with pSjD had a statistically significantly higher total Oral Health Impact Profile (OHIP) score compared to the control subjects (p < 0.001, Mann–Whitney U test). Conclusions: The patients with pSjD showed short-term hyperactivity of the HPA axis compared to the control subjects. Full article
Show Figures

Figure 1

Back to TopTop