Treatment of Alzheimer’s Disease
A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Neurology".
Deadline for manuscript submissions: closed (31 October 2021) | Viewed by 9812
Special Issue Editor
Interests: neurosciences; electron microscopy; Alzheimer’s disease; neuropathology; clinical neurology; neurophilosophy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Alzheimer’s disease (AD) is one of the most enigmatic and multidimensional neurodegenerative diseases of the brain, inducing serious mental, social, humanitarian, and economic problems. The failure of the currently available therapeutic regimes and the fatal outcome of the disease create an urgent need for neuroscientists to continue researching the etiopathological background of the disease in an attempt to create efficient therapeutic interventions. It is well known that the neuropathological pattern of AD mostly consists of selective neuronal loss, substantial morphological and morphometric alterations of the synapses, marked mitochondrial alterations, even in the initial stages of the disease, tau pathology resulting in the formation of neurofibrillary tangles (NFT), many inflammatory phenomena, alterations of brain capillaries, and various extensive extracellular deposits of Aβ peptide’s polymers, in the form of polymorphic neuritic plaques. The majority of the alterations of the organelles in Alzheimer’s disease concern the Golgi complex, the microtubules, the synaptic vesicles, and mostly the mitochondria. The pathogenetic mechanisms embrace a diverse range of hypotheses which attempt to decipher the real cause of mental decline in AD. The philosophy of this volume is the description the existing therapeutic possibilities as well as the perspectives for an effectual therapy of AD based on a concrete and clear understanding of the pathogenetic mechanisms of the disease.
Prof. Dr. Stavros J. Baloyannis
Guest Editor
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Keywords
- Alzheimer’s disease
- Treatment
- Pathogenesis
- Therapeutic factors
- Pharmaceutical research
- Quality of life
- Nonpharmaceutical therapy
- Economic parameters
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