Metabolomic Insights: Interplay between Metabolism and Immune Response in Cancer
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Cell Metabolism".
Deadline for manuscript submissions: 31 August 2025 | Viewed by 277
Special Issue Editor
Interests: cancer; immunotherapy; cancer cachexia; metabolism; metabolites
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Understanding the interplay between metabolism and the immune response in cancer is crucial for developing effective therapeutic strategies. Metabolomics, which involves the comprehensive analysis of small molecules (metabolites) within biological systems, offers a holistic view of cellular metabolism and its regulation in the context of cancer and the immune system.
In cancer, dysregulated metabolism is a hallmark feature, with altered nutrient uptake, energy production, and metabolite utilization, supporting tumor growth and progression. The immune system plays a pivotal role in cancer surveillance and defense, with immune cells capable of recognizing and eliminating cancerous cells. However, tumors often develop mechanisms to evade immune detection and suppress immune responses, creating an immunosuppressive microenvironment that facilitates tumor growth and metastasis. Metabolomic studies have uncovered intricate interactions between cancer metabolism and immune function, offering insights into the potential therapeutic targets and biomarkers.
The intention of this Special Issue is the enrichment and evolution of this research field pertaining to the interplay between metabolism and the immune response in cancer. We are pleased to invite clinicians and researchers to submit any relevant scientific work to this interesting and promising Special Issue of Metabolites.
We look forward to your contributions.
Dr. Dimitra Rafailia Bakaloudi
Guest Editor
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- metabolites
- metabolism
- cancer
- immune response
- immunotherapy
- immunometabolism
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