Advances in Microfluidics for Quantifying Cell Mechanics and Biotransport
A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B:Biology and Biomedicine".
Deadline for manuscript submissions: closed (20 August 2021) | Viewed by 16002
Special Issue Editors
Interests: non-equilibrium interfacial phenomena; structure and function of soft interfaces in meso-scale;soft matter physics; biophysics; physics of diseases; medical application; control engineering; robotics
Interests: fluid mechanics; computational biomechanics; microcirculation; (hemo)rheology; capsule; red blood cell (RBC); margination; leukocyte; platlets; circulating tumor cell (CTC); cell adhesion; drug delivery; cancer metastasis; active cell migration; brain development; GPGPU
Special Issue Information
Dear Colleagues,
Microfluidics is a fundamental but practical way to precisely manipulate and control fluids and small particles and has been widely used in various fields, including physics, engineering, medicine, biology, and chemistry. Due to recent advancements, this technology enables us to perform automated, high-throughput, and precisely controlled assays even with extremely small amounts of reagent. Quantification of the mechanical properties or microscopic responses of biological cells has led to the development of appropriate mathematical models and also to systematic computational studies, which have revealed their underlying mechanics, e.g., relationships between the stress field and cell deformation. Thus, for clarifying mechanisms or developing a deeper understanding of the microscopic biological phenomena, more detailed and statistically reliable quantification in microfluidic devices is necessary. Based on this idea, we hope that such studies will provide insight not only into cell biology but also into the precise diagnosis of, e.g., hematologic disorders.
In this Special Issue, we highlight recent advances in microfluidics for quantifying cell mechanics and biotransport phenomena, with original research papers and review papers that focus on single-cell mechanics, suspension rheology, the collective behaviors of microswimmers, the mechanical responses of cells in confined fluid flow, fundamental technologies in micro-electro-mechanical systems (MEMS), and mathematical models. We look forward to receiving your submissions.
Dr. Hiroaki Ito
Dr. Naoki Takeishi
Guest Editors
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Keywords
- microfluidics
- confined flow
- cell mechanics
- cell physiology
- mechanotransduction
- biotransport
- biorheology
- microswimmer
- microrobotics
- cell manipulation
- diagnostics
- mathematical model
- computational fluid mechanics
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