Metal-Based Complex: Preparation and Medicinal Characteristics
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Inorganic Chemistry".
Deadline for manuscript submissions: closed (31 May 2023) | Viewed by 39679
Special Issue Editors
Interests: X-ray crystallography; coordination compounds; metal-based drugs; DFT; Hirshfeld; pincer ligands
Special Issues, Collections and Topics in MDPI journals
Interests: amino acids; peptide synthesis; small bioactive molecules; pincer ligands
Special Issues, Collections and Topics in MDPI journals
Interests: drug discovery; protein–protein interaction inhibitor; organic synthesis of biological active compounds; asymmetric synthesis; X-ray single crystallography
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Metal complexes are receiving undue interest from researchers due to their diverse range of medicinal applications. Numerous metal-based drugs are proven to be highly effective as medicine, such as in the case of cisplatin, which is the most widely used anticancer drug. The successful application of cisplatin in chemotherapy has motivated researchers to synthesize more types of Pt(II) complexes and led to the research being extending to the construction of complexes based on other metals (such as palladium, silver, tin, antimony, rhodium, boron, etc.) for use as antitumor drugs. Moreover, silver sulfadiazine is being used to prevent and treat infections due to second- and third-degree burns. This is especially relevant where commercially available organic antibiotics cannot be used in treatment due to problems related to multidrug-resistant (MDR) microbes. Hence, a great deal of interest is focused on the synthesis of metal-based drugs as alternatives for the common organic antibiotics to address the issue of MDR microbes.
This Special Issue of Molecules, entitled “Metal-Based Complexes: Preparation and Medicinal Characteristics”, will cover a selection of recent research studies and review articles in the field of metal-based complexes, including their synthetic protocols and medicinal applications—including as diagnostic agents—in the context of numerous diseases, such as cancers, diabetes, and osteoporosis.
Prof. Dr. Saied Soliman
Prof. Dr. Ayman El-Faham
Prof. Dr. Assem Barakat
Guest Editors
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Keywords
- coordination chemistry
- metals in medicine
- organometallics
- anticancer agents
- antibacterial agents
- chelation therapy
- metalloantibiotics for MDR microbes
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