Coumarin and Its Derivatives III
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".
Deadline for manuscript submissions: closed (31 July 2024) | Viewed by 1794
Special Issue Editor
Interests: coumarins; natural product chemistry; organic chemistry; medicinal chemistry; chemical biology; computational chemistry
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Coumarin is a privileged scaffold in medicinal chemistry. Its derivatives are widely distributed in nature and can be found in a large number of naturally occurring and synthetic bioactive molecules. This scaffold is a unique and versatile oxygen-containing heterocyclic structure, presenting a large conjugated system with electron-rich and charge transport properties. These properties are responsible for the interaction of this scaffold with other molecules, such as biomolecules and ions. Therefore, a great number of coumarin derivatives have been designed, synthetized, and evaluated against different pharmacological targets. In addition, coumarin-based ion receptors, fluorescent probes, and biological stains are growing quickly and have extensive applications with which to monitor enzyme activity and complex biological events in a timely manner, as well as accurately monitor pharmacological and pharmacokinetic properties in living cells. The extraction, synthesis, and biological evaluation of coumarins have become extremely attractive and rapidly developing topics. Research articles, reviews, communications, and concept papers focused on the multidisciplinary profile of coumarins, highlighting natural sources, most recently synthetic pathways, along with the main biological applications and theoretical studies, are welcome for this Special Issue.
Dr. Maria João Matos
Guest Editor
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Keywords
- coumarins
- natural products
- synthesis
- bioactivity
- fluorescent dyes
- computational studies
- analytical methods
- medicinal chemistry
- chemical biology
- drug discovery
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Related Special Issues
- Coumarin and Its Derivatives II in Molecules (16 articles)
- Coumarin and Its Derivatives in Molecules (25 articles)