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Advances in Green Solvents for Analytical Chemistry: Deep Eutectic Solvents and Biosolvents

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Analytical Chemistry".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 127

Special Issue Editors


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Guest Editor
Cnr-Consiglio Nazionale delle Ricerche Instituto per i Sistemi Biologici (ISB), Rome, Italy
Interests: HPLC; nano-LC; capillary electrophoresis; electrochromatography; mass spectrometry; micro extraction; sample preparation; chiral separations; food analysis; pharmaceutical analysis
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Chemistry, Sapienza University, P.le Aldo Moro 5, 00185 Rome, Italy
Interests: eco-friendly synthesis of new sorbent materials and neoteric solvents for green sample preparation; development of sustainable sample preparation techniques; liquid chromatography; mass spectrometry; organic micronutrient profiling of foods and biological fluids; analysis of emerging contaminants in foodstuffs; environmental and biological samples
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Considering the pivotal importance of solvents in the development of analytical methods, as well as the need for sustainability in the future development of Chemistry, we are pleased to present this new Special Issue focused on green solvents for Analytical Chemistry. In recent decades, since Abbott described deep eutectic solvents (DESs) in 2003, the research on eutectic solvents and their application for analytical purposes has led to significant improvements in greening analytical procedures, as evidenced by the growing number of publications in this field. Due to the higher than usual viscosity and peculiar physico-chemical properties of eutectic solvents, their application in several fields, including the analytical one, still represents a challenge. In many cases, these difficulties have been overcome through the development of miniaturized extraction techniques. However, on the one hand, the negligible vapor pressure of eutectic mixtures is among the reasons for their green character, and on the other hand, it represents the main limitation to their use in the analytical field when there is a need to concentrate the extract or modify the solvent for better compatibility with the detection system. In such cases, a better solution seems to be the choice of a non-conventional solvent alternative to the traditional petroleum-derived solvents. Among these, biosolvents, such as naturally derived esters, are emerging solutions that are still scarcely explored in the literature.

This Special Issue addresses any eutectic liquid of analytical interest (DES, LTTM, (D)ES, NADES, etc.) and any solvent in compliance with Green Analytical Chemistry principles, collecting the latest advances in this topic and original applications in the analytical field: alternative solvents for green sample preparation in extraction procedure, as well as their use as mobile phase additives/modifiers in chromatography.

We warmly invite our colleagues to submit their original contributions—be it research manuscripts, short communications, or reviews—to this Special Issue. We believe that a comprehensive collection of the latest knowledge in this field will foster new connections among researchers and inspire innovative ideas for the sustainable development of Analytical Chemistry.

Dr. Giovanni D'Orazio
Dr. Chiara Dal Bosco
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • eutectic Solvents
  • biosolvents
  • green chemistry
  • microextraction techniques
  • environmentally friendly methods
  • green sample preparation
  • chromatography modifiers
  • sample preparation

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Published Papers

This special issue is now open for submission.
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