molecules-logo

Journal Browser

Journal Browser

Green Analytical Chemistry: From Sample Preparation to Detection

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Analytical Chemistry".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 753

Special Issue Editors


E-Mail Website
Guest Editor
Laboratory of Analytical Chemistry, School of Chemistry, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
Interests: analytical chemistry; sample preparation; chromatography; HPLC; method validation; method development; separation science; food analysis; bioanalysis; environmental analysis; green analytical chemistry; sorptive extraction; microextraction techniques
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Laboratory of Pharmaceutical Analysis, Division of Pharmaceutical Chemistry, School of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis, Zografou, 15771 Athens, Greece
Interests: pharmaceutical analysis; analytical chemistry; analytical methods; drug analysis, metabolites; bioactive compounds; pharmaceuticals; cosmeceuticals
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

After the introduction of the green chemistry concept in 1998 by Anastas and Warner, the field of green analytical chemistry was also introduced, focusing on developing analytical procedures that are more environmentally friendly and safer for both humans and the ecosystem.

Since sample preparation is and will always be the most important step in chemical analysis, inevitably, the concept of green sample preparation was proposed as a reasonable consequence following the trends of green analytical chemistry.

Recent advances in sample pre-treatment have to align with green chemistry and green analytical chemistry demands in all steps of analytical procedure, ranging from sampling and sample preparation to detection, focusing on microextraction techniques, miniaturization, and automation or semi-automation. In pharmaceutical analysis and bioanalysis, the adoption of green methodologies can significantly minimize the environmental footprint of routine testing, high-throughput workflows, and trace-level determinations, particularly in complex biological matrices such as plasma, urine, and breast milk.

Analytical scientists from all application fields are invited to share their experience and report on recent advances and new trends in accordance with green perspectives in all analytical stages.

Prof. Dr. Victoria Samanidou
Prof. Dr. Irene Panderi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • green chemistry
  • green analytical chemistry
  • green sample preparation
  • microextraction techniques
  • pharmaceutical analysis
  • bioanalysis
  • metric tools
  • miniaturization
  • automated techniques
  • sustainable analytical workflows

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Review

30 pages, 1352 KB  
Review
Green Approaches in High-Performance Liquid Chromatography for Sustainable Food Analysis: Advances, Challenges, and Regulatory Perspectives
by Eftychia G. Karageorgou, Natasa P. Kalogiouri and Victoria F. Samanidou
Molecules 2025, 30(17), 3573; https://doi.org/10.3390/molecules30173573 - 31 Aug 2025
Viewed by 491
Abstract
This review provides a comprehensive overview of the recent green innovations in high-performance liquid chromatography (HPLC) for sustainable food analysis. It outlines the principles of green analytical chemistry and examines advances such as eco-friendly solvent systems, miniaturized and energy-efficient instrumentation, and greener sample [...] Read more.
This review provides a comprehensive overview of the recent green innovations in high-performance liquid chromatography (HPLC) for sustainable food analysis. It outlines the principles of green analytical chemistry and examines advances such as eco-friendly solvent systems, miniaturized and energy-efficient instrumentation, and greener sample preparation techniques. Key applications include the analysis of bioactive compounds, detection of contaminants and residues, and support for clean-label and sustainability claims. Furthermore, the review discusses relevant regulatory and certification frameworks, including ISO 14001, ISO 22000, and global food safety initiatives aligned with environmental, social, and governance standards. Persistent challenges, such as cost, limitations in analytical performance, and limited instrument availability, are highlighted, along with the need for reliable metrics to assess the environmental impact and effectiveness of green analytical practices. The review concludes by emphasizing the need for interdisciplinary collaboration among scientists, industry stakeholders, and regulatory bodies to support the wider adoption of sustainable HPLC practices in food laboratories. Full article
(This article belongs to the Special Issue Green Analytical Chemistry: From Sample Preparation to Detection)
Back to TopTop