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Nutritional and Molecular Modulators of Vascular Inflammation and Regeneration

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Clinical Nutrition".

Deadline for manuscript submissions: 25 April 2026 | Viewed by 4

Special Issue Editor


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Guest Editor
Department of Pharmacology and Regenerative Medicine, College of Medicine, University of Illinois, Chicago, IL 60612, USA
Interests: lung injury; tissue repair; regeneration; inflammation; inflammation resolution; immune system dynamics; metabolism; metabolic reprogramming; epigenetics; epigenetic regulation
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Special Issue Information

Dear Colleagues,

Vascular inflammation and impaired regeneration are central to the pathogenesis of numerous chronic diseases, including cardiovascular disorders, diabetes, pulmonary hypertension, and age-related vascular decline. Emerging evidence highlights that both nutritional factors and molecular pathways strongly influence vascular health, not only by modulating inflammatory responses but also by orchestrating endothelial and smooth muscle cell repair, angiogenesis, and tissue remodeling. Understanding the interplay between dietary interventions, bioactives,  nutrients, and molecular regulators offers exciting opportunities for novel therapeutic strategies aimed at maintaining or restoring vascular integrity.

This Special Issue of Nutrients invites original research articles and reviews that explore the mechanisms by which nutritional and molecular modulators regulate vascular inflammation and repair. Topics of interest include—but are not limited to—dietary components (such as vitamins, polyphenols, fatty acids, and microbiome-derived metabolites), molecular pathways (such as Wnt, Notch, TGF-β, and metabolic reprogramming), and cellular players (endothelial cells, macrophages, vascular progenitors) involved in vascular repair. Studies examining translational approaches, biomarkers, or interventions that link nutrition and molecular regulation to improved vascular outcomes are especially encouraged.

By integrating insights from nutritional sciences, molecular biology, and regenerative medicine, this Special Issue aims to provide a comprehensive understanding of how diet and molecular mechanisms can be harnessed to mitigate vascular inflammation and promote regeneration. We welcome contributions from basic science, translational, and clinical studies that can contribute to the advancement of this rapidly evolving field.

Dr. Bisheng Zhou
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • vascular inflammation
  • endothelial regeneration
  • nutritional modulation
  • bioactives and nutrients
  • metabolic reprogramming
  • molecular pathways
  • angiogenesis
  • macrophage plasticity
  • vascular progenitor cells
  • cardiovascular nutrition
  • translational nutrition in vascular health
  • nutritional science and vascular biology
  • molecular nutrition and regenerative medicine
  • nutritional immunology

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Published Papers

This special issue is now open for submission.
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