The Role of Dietary Management in Chronic Inflammation
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutritional Immunology".
Deadline for manuscript submissions: 25 May 2026 | Viewed by 115
Special Issue Editors
Interests: diabetes mellitus; stem cell differentiation; regenerative medicine; stem cells; diabetes; cell culture; surgery; autoimmunity; T lymphocytes; stem cell biology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Chronic low-level inflammation is a primary driver of many chronic diseases that are significant causes of mortality and morbidity worldwide. It is a major underlying factor in the development of type 2 diabetes, heart disease, stroke, neurological conditions, and aging, leading to a significant decrease in healthspan.
Much of this inflammation is ultimately caused by dietary factors, thus offering the potential to address the root cause of many chronic diseases by dietary intervention as opposed to merely treating their symptoms with pharmacology.
Chronic low-level inflammation is often below the perception of pain. However, it can be measured by various blood markers, changes in the expression of inflammatory mediators, and changes in inflammatory gene expression. Although dietary interventions can attenuate many of these inflammatory markers, they are only one of the pillars of the healthspan ecosystem that is important to adhere to for the prevention and treatment of chronic disease. Nevertheless, they are critically important components of any realistic healthspan extension strategy.
This Special Issue aims to identify and assess dietary interventions as well as specific nutrients that can decrease the levels of chronic low-level inflammation. Furthermore, addressing the molecular mechanisms of their interventions at the level of metabolic control points at the cellular level, activation or inhibition of gene transcription factors, and epigenetic changes that the diet can induce is another goal of this Special Issue.
We wish to encourage all investigators who work in this field to contribute with original research or reviews on the molecular basis of anti-inflammatory dietary interventions to submit their work to this Special Issue to widen our knowledge and open new research pathways for using dietary interventions to treat the underlying cause of conditions associated with chronic low-level inflammation.
Prof. Dr. Camillo Ricordi
Dr. Barry Sears
Guest Editors
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Keywords
- dietary intervention
- omega-3 fatty acids
- polyphenols
- fermentable fiber
- gut barrier
- immune responses
- inflammation
- healthspan
- epigenetic changes
- gene transcription factors
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