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Exercise and Nutrition for the Promotion of Healthy Ageing

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Geriatric Nutrition".

Deadline for manuscript submissions: closed (31 May 2023) | Viewed by 4401

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Guest Editor
National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China
Interests: geriatric nutrition; chronic disease prevention and control
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In 2020, the number of people aged 60 years and older outnumbered the number of children younger than 5 years. With the fast pace of population ageing across the world, how to achieve healthy and successful ageing is a major issue. Although some of the variations in older people’s health are genetic, most are due to people’s physical and social environments—including their homes, neighborhoods, and communities, as well as their personal characteristics, such as their sex, ethnicity, or socioeconomic status. Nevertheless, exercise and nutrition are also of great significance for elders' health, and their role in promoting healthy ageing has been reported on in several studies—not only epidemiology studies but also intervention research.

This future Special Issue will collect a series of articles involving relevant topics around dietary intake, dietary pattern, physical activity and their potential associations with frailty, sarcopenia, malnutrition and some related NCD. The findings from the aforementioned studies will provide important implications for policy making, strategy development and public health practice.

Dr. Pengkun Song
Guest Editor

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Keywords

  • exercise
  • nutrition
  • geriatrics
  • aging
  • healthy ageing

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Published Papers (2 papers)

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Research

11 pages, 2850 KiB  
Article
The Role of Consumption of Molybdenum Biofortified Crops in Bone Homeostasis and Healthy Aging
by Sonya Vasto, Davide Baldassano, Leo Sabatino, Rosalia Caldarella, Luigi Di Rosa and Sara Baldassano
Nutrients 2023, 15(4), 1022; https://doi.org/10.3390/nu15041022 - 17 Feb 2023
Cited by 5 | Viewed by 2074
Abstract
Osteoporosis is a chronic disease and public health issue in aging populations. Inadequate intake of micronutrients increases the risk of bone loss during an adult’s lifespan and therefore of osteoporosis. The aim of the study was to analyze the effects of consumption of [...] Read more.
Osteoporosis is a chronic disease and public health issue in aging populations. Inadequate intake of micronutrients increases the risk of bone loss during an adult’s lifespan and therefore of osteoporosis. The aim of the study was to analyze the effects of consumption of biofortified crops with the micronutrient molybdenum (Mo) on bone remodeling and metabolism in a population of adults and seniors. The trial enrolled 42 senior and 42 adult people randomly divided into three groups that consumed lettuce biofortified with molybdenum (Mo-biofortified group) or without biofortification (control group) or molybdenum in a tablet (Mo-tablet group) for 12 days. We chose an experimental period of 12 days because the bone remodeling marker levels are influenced in the short term. Therefore, a period of 12 days allows us to determine if there are changes in the indicators. Blood samples, obtained at time zero and at the end of the study, were compared within the groups adults and seniors for the markers of bone resorption, C-terminal telopeptide (CTX) and bone formation osteocalcin, along with the markers of bone metabolism, parathyroid hormone (PTH), calcitonin, albumin-adjusted calcium, vitamin D, phosphate and potassium. Consumption of a Mo tablet did not affect bone metabolism in the study. Consumption of Mo-biofortified lettuce significantly reduced levels of CTX and PTH and increased vitamin D in adults and seniors while levels of osteocalcin, calcitonin, calcium, potassium and phosphate were not affected. The study opens up new considerations about the role of nutrition and supplementation in the prevention of chronic diseases in middle-aged and older adults. Consumption of Mo-biofortified lettuce positively impacts bone metabolism in middle-aged and older adults through reduced bone resorption and improved bone metabolism while supplementation of Mo tablets did not affect bone remodeling or metabolism. Therefore, Mo-biofortified lettuce may be used as a nutrition intervention to improve bone homeostasis and prevent the occurrence of osteoporosis in the elderly. Full article
(This article belongs to the Special Issue Exercise and Nutrition for the Promotion of Healthy Ageing)
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13 pages, 637 KiB  
Article
The Increased Risk of Hypertension Caused by Irrational Dietary Pattern May Be Associated with Th17 Cell in the Middle-Aged and Elderly Rural Residents of Beijing City, Northern China: A 1:1 Matched Case-Control Study
by Cheng Li, Yaru Li, Nan Wang, Zhiwen Ge, Zhengli Shi, Jia Wang, Bingjie Ding, Yanxia Bi, Yuxia Wang, Yisi Wang and Zhongxin Hong
Nutrients 2023, 15(2), 290; https://doi.org/10.3390/nu15020290 - 6 Jan 2023
Cited by 3 | Viewed by 1932
Abstract
An irrational diet has been widely considered as one of the vital risk factors of hypertension. Previous studies have indicated that immune dysfunction may be involved in the pathogenic process of hypertension, while fewer studies have mentioned whether CD4+ T cells are involved [...] Read more.
An irrational diet has been widely considered as one of the vital risk factors of hypertension. Previous studies have indicated that immune dysfunction may be involved in the pathogenic process of hypertension, while fewer studies have mentioned whether CD4+ T cells are involved in the association between dietary pattern and hypertension. This present 1:1 matched case-control study was conducted to analyze the association among dietary pattern, CD4+ T cells and hypertension. A total of 56 patients with diagnosed hypertension and 56 subjects without diagnosed hypertension in the rural area of Beijing City, northern China, were matched by age and gender, and then classified into a case group and a control group, respectively. Compared with the control group, higher frequencies of pro-inflammatory CD4+ T cells, such as Th1, Th1(IFN-γ), Th17(IL-17A), and Th1/17 (IFN-γ/IL-17A), were found in the case group (p < 0.05). A significantly higher level of circulating IL-17A was also found in the case group (7.4 pg/mL vs. 8.2 pg/mL, p < 0.05). Five dietary patterns were identified using exploratory factor analysis. An irrational dietary pattern, characterized by high-factor loadings of refined wheat (0.65), meat (0.78), poultry (0.76), and alcoholic beverage (0.73), was positively associated with SBP (β = 5.38, 95%CI = 0.73~10.03, p < 0.05) in the multiple linear regression model with the adjustment of potential covariates. The other dietary patterns showed no significant association with blood pressure. Furthermore, meat, processed meat, and animal viscera were positively correlated with the peripheral Th17 or Th1/17. In conclusion, the irrational dietary pattern characterized by refined wheat, meat, poultry, and alcoholic beverage, was positively correlated with blood pressure, and may increase the risk of hypertension in the rural area of Beijing, northern China. Th17, a subset of the CD4+ T helper cells, may be involved in the association between irrational dietary pattern and hypertension. Full article
(This article belongs to the Special Issue Exercise and Nutrition for the Promotion of Healthy Ageing)
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