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Ameliorating Low-Grade Inflammation through Nutrition Interventions and Exercises

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Metabolism".

Deadline for manuscript submissions: 25 December 2024 | Viewed by 1490

Special Issue Editor


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Guest Editor
1. Experimental Nutritional and Sports Medicine at Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany
2. Head of Sports Science and Performance Physiology Research Group at Hector-Center for Nutrition, Exercise and Sports, Department of Medicine 1, University Hospital Erlangen, Erlangen, Germany
Interests: exercise physiology; sports medicine; physical activity; muscle physiology; cardiorespiratory fitness; chronic diseases; nutrition; obesity; metabolic syndrome
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Special Issue Information

Dear Colleagues,

It is widely acknowledged that chronic low-grade inflammation is a central driver in the development of many non-communicable chronic diseases (NCDs), such as cardiovascular disease, type 2 diabetes, and cancer. The prevalence of these diseases has been steadily increasing over recent decades, highlighting the urgent need for effective preventive and treatment strategies. Consequently, exploring measures that can effectively counteract chronic low-grade inflammation is essential for developing targeted interventions to combat NCDs.

Healthy lifestyle habits, particularly proper nutrition and regular physical activity, have been shown to play a crucial role in the prevention and treatment of chronic diseases. There is growing evidence to suggest that dietary modifications and targeted exercise interventions can have a beneficial impact on reducing chronic low-grade inflammation.

The goal of this Special Issue is to provide an updated overview and new insights into the role of nutrition, physical activity, and exercise in preventing and treating chronic low-grade inflammation. We invite researchers to submit original research and review papers that investigate the effects of diet, nutritional supplements, physical activity, or specific exercise programs on chronic low-grade inflammation in different cohorts. Through this Special Issue, we aim to present novel discoveries in the field and foster discussions on innovative approaches for ameliorating low-grade inflammation and associated disorders through nutrition and exercise.

Prof. Dr. Dejan Reljic
Guest Editor

Manuscript Submission Information

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Keywords

  • nutrition
  • diet
  • supplements
  • physical activity
  • exercise
  • aerobic training
  • resistance training
  • low-grade inflammation
  • inflammatory state
  • chronic diseases
  • cardiovascular disease
  • obesity
  • metabolic syndrome

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Published Papers (1 paper)

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Research

11 pages, 940 KiB  
Article
Effect of Single High-Dose Vitamin D3 Supplementation on Post-Ultra Mountain Running Heart Damage and Iron Metabolism Changes: A Double-Blind Randomized Controlled Trial
by Błażej Stankiewicz, Jan Mieszkowski, Andrzej Kochanowicz, Paulina Brzezińska, Bartłomiej Niespodziński, Tomasz Kowalik, Tomasz Waldziński, Konrad Kowalski, Andżelika Borkowska, Joanna Reczkowicz, Ludmiła Daniłowicz-Szymanowicz and Jędrzej Antosiewicz
Nutrients 2024, 16(15), 2479; https://doi.org/10.3390/nu16152479 - 31 Jul 2024
Viewed by 1284
Abstract
Exercise-induced inflammation can influence iron metabolism. Conversely, the effects of vitamin D3, which possesses anti-inflammatory properties, on ultramarathon-induced heart damage and changes in iron metabolism have not been investigated. Thirty-five healthy long-distance semi-amateur runners were divided into two groups: one group [...] Read more.
Exercise-induced inflammation can influence iron metabolism. Conversely, the effects of vitamin D3, which possesses anti-inflammatory properties, on ultramarathon-induced heart damage and changes in iron metabolism have not been investigated. Thirty-five healthy long-distance semi-amateur runners were divided into two groups: one group received 150,000 IU of vitamin D3 24 h prior to a race (n = 16), while the other group received a placebo (n = 19). Serum iron, hepcidin (HPC), ferritin (FER), erythroferrone (ERFE), erythropoietin (EPO), neopterin (NPT), and cardiac troponin T (cTnT) levels were assessed. A considerable effect of ultramarathon running on all examined biochemical markers was observed, with a significant rise in serum levels of ERFE, EPO, HPC, NPT, and cTnT detected immediately post-race, irrespective of the group factor. Vitamin D3 supplementation showed a notable interaction with the UM, specifically in EPO and cTnT, with no other additional changes in the other analysed markers. In addition to the correlation between baseline FER and post-run ERFE, HPC was modified by vitamin D. The ultramarathon significantly influenced the EPO/ERFE/HPC axis; however, a single substantial dose of vitamin D3 had an effect only on EPO, which was associated with the lower heart damage marker cTnT after the run. Full article
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