Nutritional Management of Intestinal Microbiota and Related Host Health
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Prebiotics and Probiotics".
Deadline for manuscript submissions: closed (20 April 2023) | Viewed by 6657
Special Issue Editors
2. Department of Surgery, Division of Visceral and Transplantation Surgery, University Hospital Zurich, Zurich, Switzerland
Interests: gut microbiome; gastrointesitnal tract; metabolic disease; obesity; nutrition
Special Issue Information
Dear Colleagues,
The gastrointestinal (GI) tract represents one of the largest interfaces between host and environmental factors. It responds to signals originating in the 'outside lumen' including nutrients, mechanical factors, drugs, and toxins to determine whether the intraluminal content is absorbed or rejected. It also functions as central neuroendocrine, barrier and immune organ all of which is critical for overall host health and wellbeing. While the stomach and small intestine have long been thought as the main functional segments, it is now evident that also the large intestine with its microbial ecosystem is pivotal for GI physiology and host health. It is involved in several biological processes such as nutrient utilization and energy storage, resistance against infections, maturation and modulation of the immune system and support of neuroendocrine and barrier functions.
An increasing number of recent studies shows an association between human gut microbiota perturbations and pathological conditions such as inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), obesity and systemic low grade inflammation as well as mental and cognitive disorders. If these associations prove to be causative, a targeted modulation of the gut microbiota may offer not only preventative but also novel therapeutic approaches. Proof of principle of these recent developments are transplantation of entire fecal microbiota in the treatment of Clostridium difficile, as well as nutrient-based concepts including pre-, pro-, or postbiotics as well as fermented foods in the treatment of various intestinal discorders.
We invite both academic and industry researchers to contribute to this Special Issue with the aim to summarize recent advances in studies of diet and nutrients to beneficially modulate gut microbiota and related GI and overall host health.
Dr. Robert E. Steinert
Dr. Szabolcs Péter
Guest Editors
Manuscript Submission Information
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Keywords
- gut microbiota
- prebiotics
- probiotics
- postbiotics
- fermented foods
- gastrointestinal tract
