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Nutrients
Special Issues
Prenatal and Early Postnatal Nutrition to Promote Offspring's Health
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Prenatal and Early Postnatal Nutrition to Promote Offspring's Health

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition in Women".

Deadline for manuscript submissions: 25 December 2024 | Viewed by 2294

Special Issue Editor

Dr. Benazir Siddeek

E-Mail Website
Guest Editor
DOHaD Laboratory, Woman-Mother-Child Department, Division of Pediatrics, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Rue du Bugnon 27, 1011 Lausanne, Switzerland
Interests: DOHaD; nutrition; maternal; epigenetics; non-communicable diseases
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Pregnancy and infancy are windows of sensitivity to environmental clues which influence lifelong trajectories across health and disease. Qualitative or quantitative alterations of prenatal and early postnatal nutrition induce the long-term programming of offspring's risk to develop chronic diseases such as hypertension, diabetes and obesity. Early prevention, optimal perinatal nutrition and specific follow-up measures are critical in the early preservation of long-term health.

This Special Issue will focus on the prenatal and postnatal factors related to dietary approaches, food intake and composition that influence offspring health. Articles that shed light on how nutrition can modulate offspring health through epigenetics, placental function, brain development, hormonal regulations, breast milk and microbiome composition are welcome. In addition, authors are invited to submit research and reviews with an emphasis on relevant prevention and treatment strategies. We look forward to receiving your contributions.

Dr. Benazir Siddeek
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • maternal nutrition
  • postnatal nutrition
  • developmental origin of health and disease
  • chronic diseases
  • epigenetics
  • placenta
  • microbiome
  • mitochondria

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Published Papers (2 papers)

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Research

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11 pages, 488 KiB  
Article
Macronutrients in Human Milk and Early Childhood Growth—Is Protein the Main Driver?
by Jie Ma, Debra J. Palmer, Ching Tat Lai, Susan L. Prescott, Nina D’Vaz, Philip Vlaskovsky, Lisa F. Stinson, Zoya Gridneva and Donna T. Geddes
Nutrients 2024, 16(20), 3514; https://doi.org/10.3390/nu16203514 - 16 Oct 2024
Viewed by 1442
Abstract
Background: Infant growth trajectories reflect current health status and may predict future obesity and metabolic diseases. Human milk is tailored to support optimal infant growth. However, nutrient intake rather than milk composition more accurately predicts growth outcomes. Although the role of protein leverage [...] Read more.
Background: Infant growth trajectories reflect current health status and may predict future obesity and metabolic diseases. Human milk is tailored to support optimal infant growth. However, nutrient intake rather than milk composition more accurately predicts growth outcomes. Although the role of protein leverage in infant growth is unclear, protein intake is important for early infancy growth. Materials and methods: This study of exclusively breastfeeding mothers with allergies (n = 161) from the Infant Fish Oil Supplementation Study assessed relationships between intake of human milk macronutrients and infant growth. Human milk fat, protein and lactose concentrations were measured at 3 months postpartum, and infant daily intakes were estimated using an average milk intake of 800 mL/day. Results: Higher human milk protein:energy ratio was associated with higher weight-for-age z-score at 2.5 years compared to 3 months and higher body mass index-for-age z-score change (6 months to 1 year compared to 3–6 months). Maternal atopy and birth season (summer) were negatively associated with human milk lactose concentration. Passive smoke exposure was associated with reduced energy and fat concentrations and increased lactose:energy ratio. Conclusions: Our results indicate that intake of human milk macronutrients may impact early childhood growth. Full article
(This article belongs to the Special Issue Prenatal and Early Postnatal Nutrition to Promote Offspring's Health)
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Review

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23 pages, 1594 KiB  
Review
Associations of Maternal Nutritional Status and Supplementation with Fetal, Newborn, and Infant Outcomes in Low-Income and Middle-Income Settings: An Overview of Reviews
by Doris González-Fernández, Oviya Muralidharan, Paulo A. Neves and Zulfiqar A. Bhutta
Nutrients 2024, 16(21), 3725; https://doi.org/10.3390/nu16213725 - 31 Oct 2024
Viewed by 574
Abstract
Background/Objectives: Despite advances in maternal nutritional knowledge, the effect of maternal diet, micronutrient status and undernutrition, and the effect of maternal supplementation on fetal, neonatal and infant outcomes still have gaps in the literature. This overview of reviews is intended to assess the [...] Read more.
Background/Objectives: Despite advances in maternal nutritional knowledge, the effect of maternal diet, micronutrient status and undernutrition, and the effect of maternal supplementation on fetal, neonatal and infant outcomes still have gaps in the literature. This overview of reviews is intended to assess the available information on these issues and identify the main maternal nutritional factors associated with offspring outcomes in low- and middle-income countries as possible targets for public health interventions. Methods: The literature search was performed in Medline (PubMed) and Cochrane Library datasets in June 2024. Pre-specified outcomes in offspring were pooled using standard meta-analytical methods. Results: We found consistent evidence on the impact of maternal undernutrition indicated by low body mass index (BMI), mid-upper arm circumference (MUAC), and stature, but not of individual micronutrient status, on intrauterine-growth retardation, preterm birth, low birth weight, and small for gestational age, with research showing a possible effect of maternal undernutrition in later child nutritional status. Studies on micronutrient supplementation showed possible beneficial effects of iron, vitamin D, and multiple micronutrients on birthweight and/or decreasing small for gestational age, as well as a possible effect of calcium on preterm birth reduction. Interventions showing more consistent beneficial outcomes were balanced protein-energy and lipid base supplements, which demonstrated improved weight in newborns from supplemented mothers and a decreased risk of adverse neonatal outcomes. Conclusions: Further research is needed to identify the benefits and risks of maternal individual micronutrient supplementation on neonatal and further child outcomes. Full article
(This article belongs to the Special Issue Prenatal and Early Postnatal Nutrition to Promote Offspring's Health)
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