Submit to Nutrients Review for Nutrients Propose a Special Issue

Journal Browser

Prenatal Development and Nutrition Intake

Special Issue Editors
Special Issue Information
Keywords
Published Papers

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Public Health".

Deadline for manuscript submissions: closed (30 June 2020) | Viewed by 22627

Share This Special Issue

Special Issue Editor

Dr. Jessica A. Grieger

E-Mail Website
Guest Editor

Adelaide Medical School, Robinson Research Institute, University of Adelaide, Adelaide 5005, Australia
Interests: nutrition; metabolic health; pregnancy; pregnancy complications; cardiovascular disease
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Nutrients is planning a Special Issue focusing on Prenatal Development and Nutrition Intake. Nutrition during pregnancy plays a pivotal role in fetal growth and development. Overconsumption of disrectionary foods may lead to adverse pregnancy and neonatal outcomes, including gestational diabetes and macrosomia, whereas micronutrient deficiencies may contribute to preterm birth and low birth weight babies. An adverse intrauterine enviroment may have a lifelong programming effect which predisposes the baby to chronic health conditions later in life.

This Special Issue aims to bring together the latest research on the role of human nutrition, both prior to and during pregnancy, on fetal growth and development. Studies on a broad range of topics, including dietary intake, supplemental intakes, dietary recommendations, and prenatal development, programming, pregnancy complications, and future child health are warranted. Mechanistic studies assessing maternal nutrition and epigenetics will be considered.

Dr. Jessica A. Grieger
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

Pre-pregnancy nutrition
Pregnancy nutrition
Fetal growth
Prenatal development
Pregnancy outcomes
Intrauterine programming

Published Papers (5 papers)

Download All Papers

Research

Jump to: Review

14 pages, 927 KiB

Open AccessArticle

The Effect of Interactions between Folic Acid Supplementation and One Carbon Metabolism Gene Variants on Small-for-Gestational-Age Births in the Screening for Pregnancy Endpoints (SCOPE) Cohort Study

by Rhodi E. Bulloch, Clare R. Wall, Lesley M. E. McCowan, Rennae S. Taylor, Claire T. Roberts and John M. D. Thompson

Nutrients 2020, 12(6), 1677; https://doi.org/10.3390/nu12061677 - 4 Jun 2020

Cited by 17 | Viewed by 3249

Abstract

Small-for-gestational-age (SGA) is associated with significant perinatal morbidity and mortality. Our aim was to investigate gene-nutrient interactions between maternal one-carbon single nucleotide polymorphisms (SNPs) and folic acid supplement (FAS) use, and their association with SGA. Nulliparous New Zealand women with singleton pregnancy were recruited as part of the Screening for Pregnancy Endpoints prospective cohort study. Data on FAS use was collected via face-to-face interview at 15 weeks’ gestation; participants were followed prospectively and birth outcome data collected within 72 h of delivery. Participants were genotyped for MTHFR 677, MTHFR 1298, MTHFD1 1958, MTR 2756, MTRR 66 and TCN2 776 SNPs. Genotype data for at least one SNP was available for 1873 (93%) of eligible participants. Analysis showed a significant SNP-FAS interaction for MTHFR 1298 (p = 0.020), MTHFR 677 (p = 0.019) and TCN2 776 (p = 0.017) in relation to SGA: MTHFR 1298 CC variant non-FAS users had an increased likelihood [Odds Ratio (OR) = 2.91 (95% Confidence Interval (CI) = 1.52, 5.60] compared with wild-type (MTHFR 1298 AA) FAS users. MTHFR 677 variant allele carrier (MTHFR 677 CT + MTHFR 677 TT) non-FAS users had an increased likelihood [OR = 1.87 (95% CI = 1.21, 2.88)] compared to wild-type (MTHFR 677 CC) FAS users. TCN2 776 variant (TCN2 776 GG) non-FAS users had an increased likelihood [OR = 2.16 (95% CI = 1.26, 3.71)] compared with wild type homozygote + heterozygote (TCN2 776 CC + TCN2 776 CG) FAS users. No significant interactions were observed for MTHFD1 1958, MTR 2756 or MTRR 66 (p > 0.05). We observed an overall pattern of FAS attenuating differences in the likelihood of SGA seen between genotype groups in FAS non-users. Future research should focus on how intake of other one-carbon nutrients might mediate these gene-nutrient interactions. Full article

(This article belongs to the Special Issue Prenatal Development and Nutrition Intake)

► Show Figures

Figure 1

18 pages, 835 KiB

Open AccessArticle

Association between Dietary Intake of One-Carbon Metabolism Nutrients in the Year before Pregnancy and Birth Anthropometry

by Marion Lecorguillé, Sandrine Lioret, Blandine de Lauzon-Guillain, Erwan de Gavelle, Anne Forhan, François Mariotti, Marie-Aline Charles and Barbara Heude

Nutrients 2020, 12(3), 838; https://doi.org/10.3390/nu12030838 - 20 Mar 2020

Cited by 13 | Viewed by 4188

Abstract

Few studies have evaluated the role of methylation-pathway nutrients involved in fetal growth (B vitamins, choline, betaine, and methionine). These one-carbon metabolism (OCM) nutrients are essential for DNA methylation in the periconception period. We aimed to characterize dietary patterns of 1638 women from the EDEN mother-child cohort in the year before pregnancy according to the contribution of OCM nutrients and to study the association of such patterns with anthropometric measurements at birth. Dietary intake before pregnancy was assessed by using a semi-quantitative food frequency questionnaire. We used the reduced-rank regression (RRR) method to identify dietary patterns using OCM nutrients as intermediate variables. We ran linear regressions models to study the association between dietary patterns scores and birth weight, length, head circumference, gestational age, and sex-specific z-scores, adjusting for maternal characteristics and vitamin supplementation before and during pregnancy. Three patterns, “varied and balanced”, “vegetarian tendency”, and “bread and starchy food” were identified, explaining 58% of the variability in OCM nutrient intake. Higher scores on the “varied and balanced” pattern tended to be associated with higher birth length and weight. In mainly well-nourished young French women, we did not find evidence that variability in OCM nutrient intake has major effects on fetal growth. Full article

(This article belongs to the Special Issue Prenatal Development and Nutrition Intake)

► Show Figures

Figure 1

10 pages, 285 KiB

Open AccessArticle

Low Prevalence of Folic Acid Supplementation during Pregnancy: A Multicenter Study in Vietnam

by Anh Vo Van Ha, Yun Zhao, Colin W. Binns, Ngoc Minh Pham, Cong Luat Nguyen, Phung Thi Hoang Nguyen, Tan Khac Chu and Andy H. Lee

Nutrients 2019, 11(10), 2347; https://doi.org/10.3390/nu11102347 - 2 Oct 2019

Cited by 6 | Viewed by 4223

Abstract

Periconceptional folic acid (FA) supplementation is recommended to prevent neural tube defects (NTDs), but little information is known about its use in Vietnam. It is important that FA supplements start to be taken when planning a pregnancy and continued through the first trimester to prevent NTDs, as the neural tube closes in the first month of pregnancy. However, FA supplementation in Vietnam is usually recommended to commence from the first antenatal visit, which is usually at 16 weeks, and very few women take FA before their first visit. This multicenter study aimed to determine the prevalence of FA supplement use and associated maternal characteristics in Vietnam. FA supplementation was assessed in 2030 singleton pregnant women between 2015 and 2016. In total, 654 (32.2%) women reported taking either supplements containing FA alone or multivitamins containing FA, and 505 (24.9%) reported correctly taking supplements containing FA alone. Women who were aged 30 years or over, had low education levels, had formal employment, and whose current pregnancy was first or unplanned were less likely to supplement with FA. Education programs are needed to encourage FA supplementation when contemplating pregnancy. Full article

(This article belongs to the Special Issue Prenatal Development and Nutrition Intake)

12 pages, 2322 KiB

Open AccessArticle

Preconception Folic Acid Supplement Use in Immigrant Women (1999–2016)

by Roy M. Nilsen, Anne K. Daltveit, Marjolein M. Iversen, Marit G. Sandberg, Erica Schytt, Rhonda Small, Ragnhild B. Strandberg, Eline S. Vik and Vigdis Aasheim

Nutrients 2019, 11(10), 2300; https://doi.org/10.3390/nu11102300 - 27 Sep 2019

Cited by 10 | Viewed by 5117

Abstract

This study examines how preconception folic acid supplement use varied in immigrant women compared with non-immigrant women. We analyzed national population-based data from Norway from 1999–2016, including 1,055,886 pregnancies, of which 202,234 and 7,965 were to 1st and 2nd generation immigrant women, respectively. Folic acid supplement use was examined in relation to generational immigrant category, maternal country of birth, and length of residence. Folic acid supplement use was lower overall in 1st and 2nd generation immigrant women (21% and 26%, respectively) compared with Norwegian-born women (29%). The lowest use among 1st generation immigrant women was seen in those from Eritrea, Ethiopia, Morocco, and Somalia (around 10%). The highest use was seen in immigrant women from the United States, the Netherlands, Denmark, and Iceland (>30%). Folic acid supplement use increased with increasing length of residence in immigrant women from most countries, but the overall prevalence was lower compared with Norwegian-born women even after 20 years of residence (adjusted odds ratio: 0.63; 95% confidence interval: 0.60–0.67). This study suggests that immigrant women from a number of countries are less likely to use preconception folic acid supplements than non-immigrant women, even many years after settlement. Full article

(This article belongs to the Special Issue Prenatal Development and Nutrition Intake)

► Show Figures

Figure 1

Review

Jump to: Research

23 pages, 878 KiB

Open AccessReview

A Review of the Potential Interaction of Selenium and Iodine on Placental and Child Health

by Nahal Habibi, Jessica A. Grieger and Tina Bianco-Miotto

Nutrients 2020, 12(9), 2678; https://doi.org/10.3390/nu12092678 - 2 Sep 2020

Cited by 13 | Viewed by 5156

Abstract

A healthy pregnancy is important for the growth and development of a baby. An adverse pregnancy outcome is associated with increased chronic disease risk for the mother and offspring. An optimal diet both before and during pregnancy is essential to support the health of the mother and offspring. A key mediator of the effect of maternal nutrition factors on pregnancy outcomes is the placenta. Complicated pregnancies are characterized by increased oxidative stress in the placenta. Selenium and iodine are micronutrients that are involved in oxidative stress in placental cells. To date, there has been no comprehensive review investigating the potential synergistic effect of iodine and selenium in the placenta and how maternal deficiencies may be associated with increased oxidative stress and hence adverse pregnancy outcomes. We undertook a hypothesis-generating review on selenium and iodine, to look at how they may relate to pregnancy complications through oxidative stress. We propose how they may work together to impact pregnancy and placental health and explore how deficiencies in these micronutrients during pregnancy may impact the future health of offspring. Full article

(This article belongs to the Special Issue Prenatal Development and Nutrition Intake)

► Show Figures

Figure 1

Journal Menu

Journal Browser

Prenatal Development and Nutrition Intake

Share This Special Issue

Special Issue Editor

Special Issue Information

Keywords

Published Papers (5 papers)

Research

Review

Further Information

Guidelines

MDPI Initiatives

Follow MDPI