Bio-Based Materials and Personalized Medicine: Innovative Applications in Tissue Engineering and Drug Delivery

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".

Deadline for manuscript submissions: 31 August 2026 | Viewed by 1138

Special Issue Editors


E-Mail Website
Guest Editor
CICECO—Aveiro Institute of Materials, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal
Interests: polymer chemistry and technology; biodegradable polymers; nanomaterials; drug delivery systems; controlled drug release; tissue engineering

E-Mail Website
Guest Editor
Department of Pharmacognosy and Biomaterials, Poznan University of Medical Sciences, 60-806 Poznań, Poland
Interests: drug delivery systems; controlled drug release; biopolymers; mucoadhesive carrier; pharmaceutical technology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The intersection of bio-based materials and personalized medicine represents a rapidly evolving field in biomedical science, offering new pathways for individualized healthcare solutions. As the demand for more effective, patient-centered treatments has increased, the development of sustainable and biocompatible materials has become essential for advancing tissue engineering and drug delivery technologies. Bio-based materials—derived from renewable natural resources such as polysaccharides, proteins, lipids, and biodegradable polymers—exhibit inherent biocompatibility, tunable properties, and environmental sustainability, making them ideal candidates for next-generation medical applications.

In the context of tissue engineering, these materials provide structural and biochemical signals that mimic the native extracellular matrix, supporting cell adhesion, proliferation, and differentiation. This enables the fabrication of customized scaffolds and implants tailored to patients’ unique needs. Meanwhile, in drug delivery, bio-based carriers are engineered to enable the controlled, targeted, and stimuli-responsive delivery of therapeutics, enhancing treatment efficacy while minimizing side effects.

This Special Issue will explore the most recent advances in bio-based materials for personalized medicine, with a focus on their applications in tissue engineering and targeted drug delivery. We welcome researchers to contribute original research and reviews highlighting the latest material platforms developed for these purposes.

Dr. Maria Lazaridou
Dr. Magdalena Paczkowska-Walendowska
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bio-based materials
  • biocompatibility
  • sustainability
  • extracellular matrix
  • customized scaffolds
  • drug delivery
  • controlled drug delivery systems
  • tissue engineering
  • tissue regeneration
  • personalized medicine

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Review

29 pages, 1395 KB  
Review
Ionic Liquid-Enabled Drug Delivery Systems: Benefits, Limitations, and Future Perspectives
by Daeyeong Lee and Sooa Lim
Pharmaceutics 2026, 18(2), 224; https://doi.org/10.3390/pharmaceutics18020224 - 10 Feb 2026
Viewed by 739
Abstract
ILs have emerged as versatile formulation components in DDS due to their tunable physicochemical properties and ability to modulate biomolecular and interfacial interactions. This review examines IL-enabled DDS strategies across major delivery platforms, including nanocarrier-based systems, microtechnology-assisted devices, and biomacromolecule formulations, with emphasis [...] Read more.
ILs have emerged as versatile formulation components in DDS due to their tunable physicochemical properties and ability to modulate biomolecular and interfacial interactions. This review examines IL-enabled DDS strategies across major delivery platforms, including nanocarrier-based systems, microtechnology-assisted devices, and biomacromolecule formulations, with emphasis on formulation design principles rather than administration route. We discuss how ILs enhance API solubility, stability, permeability, and formulation flexibility through API–IL complex formation and controlled membrane interactions and relate mechanistic insights into IL–membrane interactions to both delivery performance and safety via structure–activity relationships. Current limitations, including toxicity concerns, lack of standardized evaluation criteria, scalability challenges, and regulatory ambiguity, are critically assessed. Overall, this review positions ILs as formulation-enabling materials rather than standalone therapeutics and underscores the importance of rational design, standardized assessment, and early regulatory alignment for advancing IL-enabled DDS toward clinical translation. Full article
Show Figures

Graphical abstract

Back to TopTop