Nanomaterials for Cancer Photothermal Therapy
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".
Deadline for manuscript submissions: closed (10 November 2021) | Viewed by 6873
Special Issue Editor
Special Issue Information
Dear Colleagues,
Nanomaterials with specific properties can reach the tumor site and produce, upon interaction with laser radiation, a temperature increase that can damage cancer cells. For this purpose, NIR light (750–1000 nm) is generally used due to its minimal interaction with biological components (e.g., water, melanin, hemoglobin, collagen), ensuring a high tissue penetration depth and reduced off-target heating. Hence, nanomaterials with a high NIR absorption (e.g., gold nanorods, graphene derivatives, transition metal dichalcogenides) have been extensively investigated for cancer photothermal therapy. On the other hand, the assembly of nanostructures with NIR-absorbing materials (e.g., ICG, IR780, polydopamine, polypyrrole) has also been explored. The nanomaterials’ photoinduced heat can also trigger other events (e.g., endosomal escape, release of encapsulated agents), opening a venue for combining nanomaterials’ mediated photothermal therapy with other therapeutic modalities (e.g., chemotherapy, gene delivery, immunotherapy).
This Special Issue of Pharmaceutics focuses on nanomaterials aimed for cancer photothermal therapy. Research articles covering the synthesis/formulation of novel NIR-light-responsive nanomaterials, their functionalization and characterization, as well as their application in cancer combination therapy are welcome. Comprehensive reviews and progress reports covering the recent advances in this field are also welcomed.
Dr. Duarte De Melo-Diogo
Guest Editor
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Keywords
- cancer
- photothermal therapy
- NIR-light-absorbing small molecules
- NIR-light-absorbing nanomaterials
- chemo-photothermal therapy
- photodynamic-photothermal therapy
- combination photothermal therapy
- 2D nanomaterials
- nanoparticles
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