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Polymers
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Molecularly Imprinted Polymers: Preparation and Application
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Molecularly Imprinted Polymers: Preparation and Application

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Polymer Applications".

Deadline for manuscript submissions: closed (5 January 2024) | Viewed by 3624

Special Issue Editors

Prof. Dr. Zhixiang Xu

E-Mail Website
Guest Editor
School of Food Science and Engineering, Shandong Agricultural University, Tai'an 271002, China
Interests: molecularly imprinted polymer; biomimetic antibody; biomimetic enzyme-linked immunassay
Dr. Jinxing He

E-Mail Website
Guest Editor
School of Food Science and Engineering, Qilu University of Technology, Jinan 250316, China
Interests: nano-magnetic materials; molecularly imprinted technique; photonic crystal; Luminescent material; rapid detection method
Dr. Yiwei Tang

E-Mail Website
Guest Editor
College of Food Science and Technology, Hebei Agricultural University, Baoding 071000, China
Interests: fluorescent probe; molecularly imprinting sensor; food safety monitoring; rapid detection; nanoparticles; analytical chemistry
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We invite the submission of research articles and reviews to a Special Issue of Polymers. For this Special Issue, we aim to present the most recent developments in the preparation and application of molecularly imprinted polymers (MIPs). The different methods of MIP preparation are within the scope of this Special Issue. Additionally, various applications of MIPs in sample preparation, electrochemical sensors, capillary electrophoresis, immunoassays, and many other fields also are within the scope of this Special Issue.

Prof. Dr. Zhixiang Xu
Dr. Jinxing He
Dr. Yiwei Tang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • molecularly imprinted polymers
  • molecular imprinting technology
  • molecularly imprinted adsorbent
  • recognition element
  • biomimetic antibody
  • synthetic receptor

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Published Papers (2 papers)

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Research

11 pages, 1257 KiB  
Article
Benzylfentanyl as a Surrogate Template for Fentanyl-Selective Imprinted Polymers
by Md. Ragib Hasan and David A. Spivak
Polymers 2023, 15(18), 3669; https://doi.org/10.3390/polym15183669 - 6 Sep 2023
Viewed by 1160
Abstract
The illicit use of fentanyl has led to hundreds of thousands of opioid-related deaths worldwide. Therefore, the detection of fentanyl by law enforcement and recreational users is of utmost importance. However, current detection methods are expensive, time-consuming, require special storage conditions, and necessitate [...] Read more.
The illicit use of fentanyl has led to hundreds of thousands of opioid-related deaths worldwide. Therefore, the detection of fentanyl by law enforcement and recreational users is of utmost importance. However, current detection methods are expensive, time-consuming, require special storage conditions, and necessitate complex instrumentation that is generally unportable and requires skilled personnel to operate. An alternative approach would be using molecularly imprinted polymers (MIPs) as the recognition component of a handheld sensor, testing strip, or color-based assay. In this work, a molecularly imprinted polymer was constructed using the functional monomer methacrylic acid (MAA) and the cross-linking monomer ethyleneglycol dimethacrylate (EGDMA), with benzylfentanyl (Bfen) as the template. The use of benzylfentanyl is advantageous because it closely mimics fentanyl’s structure but does not cause any physiological narcotic effects. Important studies herein determined the optimum ratio of the template/functional monomer, with subsequent evaluations of selectivity of the MIP for the template and fentanyl versus the commonly encountered narcotics such as methamphetamine, cocaine, and heroin. The data obtained from the HPLC analysis showed that the Bfen-MIP was successful in selectively binding the template and actual fentanyl, better than other common narcotics. Full article
(This article belongs to the Special Issue Molecularly Imprinted Polymers: Preparation and Application)
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11 pages, 3631 KiB  
Article
Development of an Immunoassay Method for the Sensitive Detection of Histamine and Tryptamine in Foods Based on a CuO@Au Nanoenzyme Label and Molecularly Imprinted Biomimetic Antibody
by Xinli Peng, Yongfeng Chen, Chunhui Gao, Yufeng Sun, Geoffrey I. N. Waterhouse and Zhixiang Xu
Polymers 2023, 15(1), 21; https://doi.org/10.3390/polym15010021 - 21 Dec 2022
Cited by 7 | Viewed by 1841
Abstract
In this paper, a novel biomimetic enzyme-linked immunoassay method (BELISA) was successfully established for the detection of histamine and tryptamine, based on catalytically active cupric oxide@gold nanoparticles (CuO@Au NPs) as a marker and a molecularly imprinted polymer (MIP) as the biomimetic antibody. Under [...] Read more.
In this paper, a novel biomimetic enzyme-linked immunoassay method (BELISA) was successfully established for the detection of histamine and tryptamine, based on catalytically active cupric oxide@gold nanoparticles (CuO@Au NPs) as a marker and a molecularly imprinted polymer (MIP) as the biomimetic antibody. Under optimized conditions, the detection limitations of the BELISA method for histamine and tryptamine were 0.04 mg L−1 and 0.14 mg L−1, respectively. For liquor spiked with histamine and tryptamine, the BELISA method delivered satisfactory recoveries ranging from 89.90% to 115.00%. Furthermore, the levels of histamine and tryptamine in fish, soy sauce, and rice vinegar samples were detected by the BELISA method and a high performance liquid chromatography method, with no significant difference between the two methods being found. Although the catalytic activity of nanozymes is still lower than that of natural enzymes, the BELISA method could still sensitively determine the histamine and tryptamine levels in food samples. Full article
(This article belongs to the Special Issue Molecularly Imprinted Polymers: Preparation and Application)
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