Antioxidant Properties of Medicinal Plants

A special issue of Processes (ISSN 2227-9717). This special issue belongs to the section "Pharmaceutical Processes".

Deadline for manuscript submissions: closed (28 February 2022) | Viewed by 9916

Special Issue Editors


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Guest Editor
Department of Virology, Medical University of Lublin, 20-093 Lublin, Poland
Interests: antiviral activity of natural products and synthesized compounds; cytotoxicity of natural products and synthesized compounds on normal and cancer cell lines; oxidative stress, total antioxidant status (TAS); the activities of glutathione peroxidase (GPx) and superoxide dismutase (SOD) in cancer associated with viral infection and diabetic patients

E-Mail Website1 Website2
Guest Editor
Department of Virology, Faculty of Medicine, Medical University, Chodźki 1, 20-093 Lublin, Poland
Interests: phytochemistry and biological activity of natural products; in vitro evaluation of cytotoxicity of natural products, synthesized compounds, and medical materials on normal and cancer cell lines; virus culturing techniques; antiviral activity of natural products and synthesized compounds; the use of molecular biology

E-Mail Website
Guest Editor
Department of Virology, Faculty of Medicine, Medical University, Chodźki 1, 20-093 Lublin, Poland
Interests: oxidative stress, total antioxidant status (TAS); the activities of glutathione peroxidase (GPx) and superoxide dismutase (SOD) in cancer associated with viral infection and diabetic patients

Special Issue Information

Dear Colleagues,

Free radicals are responsible for oxidative stress in a human body, which has been associated with a variety of diseases including cancer, cardiovascular diseases, and diabetes, as well as Alzheimer’s disease, Parkinson’s disease, and other neurodegenerative diseases. There is plenty of research published describing antioxidant molecules, both natural and synthetic, that have been shown to prevent formation of free radicals or to scavenge excessive amounts already formed and counteract oxidative stress in laboratory experiments using ex vivo, in vitro and in vivo experiments. However, it still remains uncertain whether supplementing our diet with those substances actually benefits our health. Moreover, the current trend to consume food supplements enriched with antioxidants raises concerns about their safety, and some researchers point out that excessive doses of antioxidants may even be harmful.

Medicinal plants are an abundant source of antioxidant molecules including flavonoids, tannins, phenols, and lignans and are often used both as a part of traditional medicine and also as important constituents of a variety of food supplements in many countries all over the world.

This Special Issue on “Antioxidant Properties of Medicinal Plants” aims to present advances in the studies of antioxidant properties of medicinal plants with a special emphasis on the actual benefits those properties may have on a human body, as well as on the safety of consuming food supplements enriched with antioxidants. Topics include but are not limited to:

  • Antioxidant properties of medicinal plants;
  • The influence of antioxidants present in medicinal plants on the human body;
  • Prevention of diseases associated with oxidative stress using medicinal plants;
  • Safety of consuming food supplements enriched with natural antioxidants.

Prof. Dr. Małgorzata Polz-Dacewicz
Dr. Łukasz Świątek
Dr. Ewa Kliszczewska
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Processes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Antioxidant properties
  • Disease prevention
  • Food supplements
  • Medicinal plants
  • Natural antioxidants
  • Oxidative stress

Published Papers (3 papers)

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Research

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10 pages, 1515 KiB  
Article
Protective Effects of Chlorogenic Acid against Carbon Tetrachloride-Induced Hepatotoxicity in Mice
by Yu-Wen Hsu, Ya-Yu Chen and Chia-Fang Tsai
Processes 2022, 10(1), 31; https://doi.org/10.3390/pr10010031 - 24 Dec 2021
Cited by 7 | Viewed by 2109
Abstract
The protective effects of chlorogenic acid (CGA) against liver injury were evaluated by its reduction in carbon tetrachloride (CCl4)-induced hepatic damage in ICR mice. The animals were orally given CGA (60, 100, and 200 mg/kg, respectively) or silymairn (200 mg/kg) daily [...] Read more.
The protective effects of chlorogenic acid (CGA) against liver injury were evaluated by its reduction in carbon tetrachloride (CCl4)-induced hepatic damage in ICR mice. The animals were orally given CGA (60, 100, and 200 mg/kg, respectively) or silymairn (200 mg/kg) daily with 0.3% CCl4 administration (3 mL/kg, dissolved in olive oil) after medicament treatment on the 7th day. Compared with the normal group, CCl4 caused severe impairment in liver according to the evidence of significant reduction in the level of total albumin and expansion (p < 0.05) of the activities in aspartate aminotransferase (AST) and alanine aminotransferase (ALT), cholesterol, triglyceride (TG), and total albumin in serum, decreased the level of glutathione (GSH), and diminished the activities of catalase, superoxide dismutase (SOD), glutathione reductase (GSH-Rd), and glutathione peroxidase (GSH-Px) in liver while increasing the level of hepatic thiobarbituric acid-reactive substances (TBARS). However, oral administration of CGA or silymarin could significantly (p < 0.05) decrease the serum levels of AST, ALT, cholesterol, TG, and total albumin and elevated the serum total albumin and the activities of GSH, catalase, SOD, GSH-Rd, and GSH-Px while leading to decline the TBARS in liver compared with CCl4-intoxicated group. Moreover, histopathology displayed that CGA decreased the formation of lesions in liver resulted from CCl4. The outcomes indicate that CGA shows the efficiency hepatoprotective consequences for CCl4-incited liver injuries in mice by the elevation of the activities of antioxidant enzymes and hindrance of lipid peroxidation. Full article
(This article belongs to the Special Issue Antioxidant Properties of Medicinal Plants)
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15 pages, 851 KiB  
Article
Sage (Salvia officinalis L.) Essential Oil as a Potential Replacement for Sodium Nitrite in Dry Fermented Sausages
by Branislav Šojić, Vladimir Tomović, Jovo Savanović, Sunčica Kocić-Tanackov, Branimir Pavlić, Marija Jokanović, Ardea Milidrag, Aleksandra Martinović, Dragan Vujadinović and Milan Vukić
Processes 2021, 9(3), 424; https://doi.org/10.3390/pr9030424 - 26 Feb 2021
Cited by 13 | Viewed by 2832
Abstract
This study investigates the effects of sodium nitrite replacement by the sage essential oil (SEO), on the physico-chemical, microbiological and sensory quality of dry fermented sausages (DFS) during 225 days of storage. The SEO (0.00, 0.05 and 0.10 µL/g) was added in DFS [...] Read more.
This study investigates the effects of sodium nitrite replacement by the sage essential oil (SEO), on the physico-chemical, microbiological and sensory quality of dry fermented sausages (DFS) during 225 days of storage. The SEO (0.00, 0.05 and 0.10 µL/g) was added in DFS batters formulated with different levels of pork back fat (15% and 25%) and sodium nitrite (0, 75 and 150 mg/kg). The inclusion of SEO had no negative impact on pH, color (instrumental and sensory) and texture parameters. Total plate counts were lower than 6 log CFU (colony forming units)/g in all samples throughout the storage. Furthermore, the addition of SEO at concentration of 0.05 µL/g provided acceptable TBARS (2-Thiobarbituric acid reactive substances) values (<0.3 mg MDA (malondialdehyde)/kg) in the samples produced with reduced levels of sodium nitrite (0 and 75 mg/kg) without negative alternations on sensory attributes of odor and flavor. Generally, our findings confirmed that the usage of SEO could be a good solution to produce healthier DFS with reduced levels of sodium nitrite. Full article
(This article belongs to the Special Issue Antioxidant Properties of Medicinal Plants)
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20 pages, 11485 KiB  
Review
An Overview of the Potential of Medicinal Plants Used in the Development of Nutraceuticals for the Management of Diabetes Mellitus: Proposed Biological Mechanisms
by Muhanad Alhujaily, Wissal Dhifi and Wissem Mnif
Processes 2022, 10(10), 2044; https://doi.org/10.3390/pr10102044 - 10 Oct 2022
Cited by 3 | Viewed by 4046
Abstract
Diabetes mellitus (DM) is a chronic metabolic disorder in which the pancreas does not produce enough insulin or the body cannot effectively use it. The prevalence of diabetes is increasing steadily, making it a global public health problem. Several serious complications are associated [...] Read more.
Diabetes mellitus (DM) is a chronic metabolic disorder in which the pancreas does not produce enough insulin or the body cannot effectively use it. The prevalence of diabetes is increasing steadily, making it a global public health problem. Several serious complications are associated with this disease. There are a number of different classes of antidiabetic medications. Interestingly, traditional medicine can also be used for the development of novel classes of hypoglycemic therapeutics. This article summarizes an update of the potential of various important medicinal plants used in the development of nutraceuticals for the management of diabetes mellitus, and a proposal of their biological mechanisms. Full article
(This article belongs to the Special Issue Antioxidant Properties of Medicinal Plants)
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