Development of In Vitro Disease Modelling
A special issue of Processes (ISSN 2227-9717). This special issue belongs to the section "Biological Processes and Systems".
Deadline for manuscript submissions: closed (15 April 2021) | Viewed by 19330
Special Issue Editor
Interests: DNA extraction; tissue engineering; protein purification; cell culture; vascular tissue engineering; biomaterials; induced pluripotent stem cells; disease modeling; skin regeneration and wound healing
Special Issue Information
Dear Colleagues,
Most of the current research focuses on understanding the cellular and molecular mechanisms of human disease pathophysiology to develop innovative and improved therapies or diagnostic tools. While small-animal models, such as transgenic mice, have been designed to achieve diseased states, they fail to completely recreate the pathogenesis as seen in humans because of their differences in gene, phenotype, and physiology with respect to humans. Furthermore, animal models would not be helpful in investigating conditions that are highly dependent on the genetic, epigenetic, or microbiome make-up of a human individual. The milestones achieved within the field of stem cell biology and tissue engineering over the last few decades have revolutionized the field of disease modeling and have the potentials to establish in vitro models from human diseased tissue that can demonstrate relevant degenerative mechanisms. In this Special Issue, we welcome both research and review manuscripts targeted towards disease modeling using engineering and stem cell approaches including , but not limited to, in vitro models of diseases of the heart, lung, intestine, liver, kidney, cartilage, skin, and vascular, endocrine, musculoskeletal, and nervous systems, as well as models of infectious diseases and cancer. We also encourage manuscripts on the use of human inducible pluripotent stem cells to recreate diseases in a dish.
Dr. Biraja Dash
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Processes is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- In vitro disease models
- Stem cells
- Induced pluripotent stem cells
- Tissue engineering
- Organ-on-a-chip
- Microfluidic devices
- 3D culture
- Drug screening
- CRISPR
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.