Vaccine Efficacy and Safety in Transplant Recipients
A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Vaccine Efficacy and Safety".
Deadline for manuscript submissions: 31 January 2025 | Viewed by 229
Special Issue Editor
Interests: immunology; immunodeficiency; vaccination; pneumococcal pneumonia; SARS-CoV-2
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The immune system offers protection against bacterial, viral, and other infections. The immune system, however, may be inadequate in offering complete protection upon its first encounter with highly virulent micro-organisms such as tetanus or SARS-CoV-2. For these cases, the immune system response can be improved through vaccination with relevant antigens from these pathogens. Vaccination induces specific antibodies and effector T-cells, as well as memory B- and T-cells, which offer long-term protection. Successful vaccination does depend on an intact immune system of the host. Transplant recipients are treated with immunosuppressive drugs to prevent the rejection of the transplanted organ. As a consequence, regular vaccines, administered at regular doses and intervals, may not be as effective as in healthy individuals. Because of this immunosuppressive treatment, transplant recipients have a higher infection risk but, at the same time, can show a poorer response to vaccination. Therefore, the optimal timing and dosing of vaccination is of utmost importance. We would like to encourage submissions to this Special Issue regarding recent advances in the optimization of the vaccination response in transplant recipients, referring to transplants in the broadest sense of the word. Adding new information on this subject may lead to a better understanding of the critical determinants of an effective immune response to vaccination and may aid in the design of optimal vaccination strategies for transplant recipients.
Prof. Dr. Ger Rijkers
Guest Editor
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Keywords
- transplant recipients
- vaccination
- kidney
- heart
- lung
- stem cell transplants
- safety
- antibody response
- efficacy
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